Faculty Details

Faculty Details

  • Name: Prof Bramanandam Manavathi
  • Mail: manavathibsluohyd.ernet.in
  • Contact: 914023134546
  • Area Of Research:Cell Biology and Cancer Biology- Our main focus is on understanding the tumor metastasis using breast cancer as a model system. We tried to address how cellular plasticity and tumor heterogeneity contributes to breast cancer development. We further investigate the molecular mechanisms and signaling pathways which contribute to the cellular plasticity and therefore serve as therapeutic targets in breast cancer.


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2 Khumukcham SS, Samanthapudi VSK, Penugurti V, Kumari A, PS Kesavan, Velattoru LR, Kotla SR, Majumder A and Manavathi B. (2019) , Hematopoietic PBX-interacting protein is a substrate and inhibitor of APC/C-Cdc20 and regulates mitosis by stabilising cyclin B1. , J Biol Chem, ASBMB,294(26),,10236-10252.IF - 4.0.
1 Guntuku L, Gangasani JK; Thummuri D; Borkar RM; Manavathi B; Ragampeta S; Vaidya JR; Sistla R;VJM Naidu (2019) , IITZ-01, a novel lysosomotropic autophagy inhibitor, has single agent antitumor efficacy in triple negative breast cancer in vitro and in vivo. , Oncogene , nature publishing group,38(4),,581-595IF - IF: 7.5.
Title Year Duration Amount(In Lakhs) PI/I
Nucleolus in control of breast tumor heterogeneity 2019 3 94.97 Prof. Bramanandam Manavathi (PI); Prof. H.A.Nagarajaram (Co-PI)