Faculty
Faculty Details
Faculty Details
Prof. Ravi Gutti holds a Ph.D. in Molecular Biology and Biotechnology from Indian Agricultural Research Institute, New Delhi. He has extensive research and teaching experience from Harvard Medical School (USA), National Institutes of Health (USA), Moffitt Cancer and Research Center (USA) and RWTH Aachen (Germany). His expertise is in gene regulation and stem cell biology. His current research is focused on understanding the molecular regulation of developmental megakaryocytopoiesis (platelet production) with emphasis on the role of non-coding RNA. He would like to explore the mechanisms regulating the developmental changes in miRNA and lncRNA expression, which are currently not understood.
Academic and Research Exposure· Professor- Dept. of Biochemistry, School of Life Sciences, University of Hyderabad (2018)
· Associate Professor–Dept. of Biochemistry, School of Life Sciences, University of Hyderabad (2016)
· Assistant Professor–Dept. of Biochemistry, School of Life Sciences, University of Hyderabad (2010)
· Instructor & Sr. Res. Fellow –Dana-Farber Cancer Institute, Harvard Medical School, USA (2010)
· Instructor & Sr. Res. Fellow –Children’s Hospital Boston, Harvard Medical School, USA (2008)
· Sr. Post Doctoral Fellow- NICHD, NIH, Bethesda, USA (2004)
. Post Doctoral Fellow – Moffitt Cancer Center, University of S. Florida, Tampa, USA (2003)Education
PhD Molecular Biology and Biotechnology-New Delhi (2003)
MSc Biotechnology- UoH Hyderabad (1997)
BSc Biochemistry-Andhra University (1995)Awards
2023 Contribution Award by the Korean Society of Hematology
2022 Global Investigator Award by Korean Society of Laboratory Medicine
2022 Overseas Contribution Award by Korean Bone Marrow Transplantation Society
2021 Global Investigator Award by Korean Society of Laboratory Medicine, Seoul
2020 “Fellow of the Telangana Academy of Sciences (FTAS)” for the year 2019 in Medical Sciences.
2019 International Assoc. for Comparative Research on Leukemia and Related Diseases Award
2019 Japanese Society of Hematology Award, Tokyo
2019 Korean Society of Hematology Award, Seoul
2018 Chancellor’s Award, University of Hyderabad, India
2018 Korean Society of Laboratory Medicine Award, Seoul
2017 Royal Society Award (UK) for Established Scientists.
2015 ICMR Venkoba Rao Award-Physiology (2012)
2012 Innovative Young Biotechnologist Award (IYBA-DBT)
2008 American Society for Biochemistry and Molecular Biology (ASBMB) Postdoctoral Fellowship, USA
2004 NIH Postdoctoral Fogarty Fellowship, NICHD, Bethesda, MD, USA
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Students/Projects Trainees
| Name | Joined As | Contact | |
|---|---|---|---|
| Shekhar Baki | PhD Student | shekharbaki2015@gmail.com | 7095960021 |
| Mahesh Malleswarapu | PhD Student | biomahi369@gmail.com | 919866108001 |
| Srividya Velagapudi | International Senior Researcher (Indo-Swiss Collaboration) | srividya.velagapudi@uzh.ch | 919381452246 |
| Vijay Prasad Koppineedi | PhD Student | nehemiahvijay2000@gmail.com | 9347154591 |
| Pallavi Saxena | PhD Student | 22lbph12@uohyd.ac.in | --- |
| Anjani Alluri | IoE Postdoctoral Fellow | anjanialluri9@gmail.com | --- |
| N Vijay Prasad | PhD Student | dr.vijaynehemiah@gmail.com | 9347154591 |
Former Students/Projects Trainees
| Name | Joined As | Working |
|---|---|---|
| Sanjeev Raghuwanshi | PhD Student | Currently in University of Illinois College of Medicine, Chicago, USA |
| Narasaiah Kovuru | PhD Student | Currently in Prof. Peter Kurre Laboratory, Perelman School of Medicine, University of Pennsylvania, USA |
| Durga Shankar Sharma | PhD Student | Currently at Dept of Pharmacology, University of Michigan, USA |
| Swati Dahariya | PhD Student | Baylor College of Medicine, TX, USA |
| Dushyant Kumar | PhD Student | |
| Indira Paddibhatla | WOS-A Scientist | Johns Hopkins University, Baltimore, USA |
| Ram Babu Undi | PhD Student | University of Oklahoma Health Sciences Center, USA |
| Ravinder Kandi | PhD Student | IRBM, Helmholtz Munich, Germany |
| Shilpa Sarvothaman | MSc Project Student | Clinical project coordinator |
| Som Dutta Paul | MSc Biochemistry Project Student | PhD Student in Genome, Cell and Developmental Biology Graduate Program at Indiana University, USA |
| Aishwarya Jaiswal | MSc Biochemistry Project Student | Currently doing PhD in Jawaharlal Nehru University, New Delhi under Prof. Rana |
| Vikas Arige | MSc Biochemistry Project Student | Complete PhD from IIT Madras and currently pursuing Postdoc at University of Rochester |
| Rashi Agarwal | BTech Project Student | Currently pursuing PhD from EMBL Hiedelberg, Germany |
| Mohit Mishra | MSc Biochemistry Project Student | Currently pursuing PhD from Jawaharlal Nehru University, New Delhi under Prof. Rakesh Bhatnagar (Vice Chancellor of BHU) |
| Pooja Ram Mohan | MSc Project Student | Worked at Enzene Biosciences, Pune and currently working in Amrita fertility centre, Ernakulam |
| Itishri Sahu | PhD Student | Currently working in University Clinic Tuebingen, Germany |
| Satya Ratan Pasupuleti | MTech Project Student and Junior Research Fellow | Currently working for food corporation of india |
| Aneesh Kotipalli | DBT-IYBA JRF | Currently working for Centre for Development of Advanced Computing (C-DAC), Pune |
| Santosh Kumar | MSc Biochemistry Project Student | Currently a PhD student in Dr. Seems Mishra Laboratory of Computational Biology at University of Hyderabad |
| Priyanka Bansal | MSc Biochemistry Project Student | Currently pursuing PhD in Dr. Christoph F kurat Laboratory in Biomedical Center (BMC), Department of Molecular Biology, LMU, Munich, Germany |
| Priyanka Dahate | MSc Biochemistry Project Student | PhD position in ZMBH, Heidelberg University, Heidelberg in Claudio Joazeiro's group. |
| Sahana A | MSc Student | PhD Student at Dr. David Stegner Laboratory in RUDOLF VIRCHOW CENTER FOR INTEGRATIVE AND TRANSLATIONAL BIOIMAGING |
| Anjali Sangeeth | PhD Student | University of Dayton, Ohio, USA |
| Shouvik Bhattacharya | MSc Student | Junior Research Fellow at TIFR Hyderabad |
| 81 | Gutti, Ravi Kumar., (2024) , Hematopoiesis: Biochemical, Cellular, Molecular, and Genomic Perspectives , , CRC Press,,,. |
| 80 | Dahariya, Swati., Velidandi, Aditya., Gautam, Dushyant Kumar., Gutti, Ravi Kumar., Paddibhatla, Indira., (2024) , IncRNAs in Leukemia , Hematopoiesis, Apple Academic Press,,,193-228. |
| 79 | Dahariya, Swati., Raghuwanshi, Sanjeev., Gutti, Ravi Kumar., (2024) , Systems Biology Approaches Toward Understanding Human Long Noncoding RNA in Hematopoietic Cells , Hematopoiesis, Apple Academic Press,,,125-142. |
| 78 | Gautam, Dushyant Kumar., Chimata, Anuradha Venkatakrishnan., Gutti, Ravi Kumar., Paddibhatla, Indira., (2024) , Investigative Tools to Study Blood Cells: A Focus on Single Cell Isolation and Analysis , Hematopoiesis, Apple Academic Press,,,19-49. |
| 77 | Dwivedi, Yogesh K., Jeyaraj, Anand., Hughes, Laurie., Davies, Gareth H., Ahuja, Manju., Albashrawi, Mousa Ahmed., Al-Busaidi, Adil S., Al-Sharhan, Salah., Al-Sulaiti, Khalid Ibrahim., Altinay, Levent., (2024) , “Real impact”: Challenges and opportunities in bridging the gap between research and practice–Making a difference in industry, policy, and society , International Journal of Information Management, Pergamon,,,102750. |
| 76 | Sangeeth, Anjali., Malleswarapu, Mahesh., Mishra, Amit., Gutti, Ravi Kumar., (2023) , Long Non-coding RNAs as Cellular Metabolism and Haematopoiesis Regulators , Journal of Pharmacology and Experimental Therapeutics, American Society for Pharmacology and Experimental Therapeutics,384,1,79-91. |
| 75 | Dahariya, Swati., Raghuwanshi, Sanjeev., Thamodaran, Vasanth., Velayudhan, Shaji R., Gutti, Ravi Kumar., (2023) , Role of Long Non-Coding RNAs in Human-Induced Pluripotent Stem Cells Derived Megakaryocytes: A p53, HOX Antisense Intergenic RNA Myeloid 1, and miR-125b Interaction Study , Journal of Pharmacology and Experimental Therapeutics, American Society for Pharmacology and Experimental Therapeutics,384,1,92-101. |
| 74 | Jagtap, Yuvraj Anandrao., Kumar, Prashant., Kinger, Sumit., Dubey, Ankur Rakesh., Choudhary, Akash., Gutti, Ravi Kumar., Singh, Sarika., Jha, Hem Chandra., Poluri, Krishna Mohan., Mishra, Amit., (2023) , Disturb mitochondrial associated proteostasis: Neurodegeneration and imperfect ageing , Frontiers in Cell and Developmental Biology, Frontiers,11,,1146564. |
| 73 | Kumar, Prashant., Choudhary, Akash., Kinger, Sumit., Jagtap, Yuvraj Anandrao., Dubey, Ankur Rakesh., Gutti, Ravi Kumar., Chitkara, Deepak., Suresh, Anil K., Mishra, Amit., (2023) , Proteostasis defects: Medicinal challenges of imperfect aging & neurodegeneration , Translational Medicine of Aging, Elsevier,,,. |
| 72 | Malleswarapu, Mahesh., Kovuru, Narasaiah., Khan, Nooruddin., Mishra, Amit., Gutti, Ravi Kumar., (2023) , Significance of TLR2 signaling during megakaryocyte development: regulatory cross-talk of miR-125b, cytokine induction, and MAPK pathway during dengue infection , American Journal of Translational Research, e-Century Publishing Corporation,15,10,5972. |
| 71 | Kumar, Prashant., Kinger, Sumit., Dubey, Ankur Rakesh., Jagtap, Yuvraj Anandrao., Choudhary, Akash., Prasad, Amit., Jha, Hem Chandra., Dhiman, Rohan., Gutti, Ravi Kumar., Mishra, Amit., (2023) , Trehalose Promotes Clearance of Proteotoxic Aggregation of Neurodegenerative Disease-Associated Aberrant Proteins , Molecular Neurobiology, Springer US,,,1-19. |
| 70 | Bhattacharya, Mrinnanda., Gutti, Ravi Kumar., (2022) , Non-coding RNAs: are they the protagonist or antagonist in the regulation of leukemia? , American Journal of Translational Research, e-Century Publishing Corporation,14,3,1406. |
| 69 | Amanullah, Ayeman., Upadhyay, Arun., Dhiman, Rohan., Singh, Sarika., Kumar, Amit., Ahirwar, Dinesh Kumar., Gutti, Ravi Kumar., Mishra, Amit., (2022) , Development and challenges of diclofenac-based novel therapeutics: targeting cancer and complex diseases , Cancers, MDPI,14,18,4385. |
| 68 | Sangeeth, Anjali., Malleswarapu, Mahesh., Mishra, Amit., Gutti, Ravi K., (2022) , Long Non-coding RNA Therapeutics: Recent Advances and Challenges , Current Drug Targets, Bentham Science Publishers,23,16,1457-1464. |
| 67 | Dubeya, Ankur Rakesh., Mishraa, Ribhav., Sundariaa, Naveen., Jagtapa, Yuvraj Anandrao., Kumara, Prashant., Kingera, Sumit., Choudharya, Akash., Jhab, Hem Chandra., Prasadc, Amit., Guttid, Ravi Kumar., (2022) , Resveratrol Promotes LRSAM1 E3 Ubiquitin Ligase-Dependent Degradation of Misfolded Proteins Linked with Neurodegeneration , Cell Physiol Biochem, ,56,,530-545. |
| 66 | Dahariya, Swati., Raghuwanshi, Sanjeev., Thamodaran, Vasanth., Velayudhan, Shaji R., Gutti, Ravi Kumar., (2022) , Role of Long non-coding RNAs in Human Induced Pluripotent Stem Cells derived Megakaryocytes: A p53, HOTAIRM1 and miR-125b interaction study , Journal of Pharmacology and Experimental Therapeutics, American Society for Pharmacology and Experimental Therapeutics,,,. |
| 65 | Sharma, Durga Shankar., Raghuwanshi, Sanjeev., Kovuru, Narasaiah., Dahariya, Swati., Gautam, Dushyant Kumar., Paddibhatla, Indira., Gutti, Ravi Kumar., (2021) , Virodhamine, an endocannabinoid, induces megakaryocyte differentiation by regulating MAPK activity and function of mitochondria , Journal of Cellular Physiology, ,236,2,1445-1453. |
| 64 | Kovuru, Narasaiah., Raghuwanshi, Sanjeev., Sangeeth, Anjali., Malleswarapu, Mahesh., Sharma, Durga Shankar., Dahariya, Swati., Pallepati, Adithya., Gutti, Ravi Kumar., (2021) , Co-stimulatory effect of TLR2 and TLR4 stimulation on megakaryocytic development is mediated through PI3K/NF-ĸB and XBP-1 loop , Cellular Signalling, Pergamon,80,,109924. |
| 63 | Gautam, Dushyant Kumar., Chimata, Anuradha Venkatakrishnan., Gutti, Ravi Kumar., Paddibhatla, Indira., (2021) , Comparative hematopoiesis and signal transduction in model organisms , Journal of Cellular Physiology, ,236,8,5592-5619. |
| 62 | Sharma, Durga Shankar., Paddibhatla, Indira., Raghuwanshi, Sanjeev., Malleswarapu, Mahesh., Sangeeth, Anjali., Kovuru, Narasaiah., Dahariya, Swati., Gautam, Dushyant Kumar., Pallepati, Aditya., Gutti, Ravi Kumar., (2021) , Endocannabinoid system: Role in blood cell development, neuroimmune interactions and associated disorders , Journal of Neuroimmunology, Elsevier,353,,577501. |
| 61 | Dahariya, Swati., Raghuwanshi, Sanjeev., Sangeeth, Anjali., Malleswarapu, Mahesh., Kandi, Ravinder., Gutti, Ravi Kumar., (2021) , Megakaryoblastic leukemia: a study on novel role of clinically significant long non-coding RNA signatures in megakaryocyte development during treatment with phorbol ester , Cancer Immunology, Immunotherapy, Springer Berlin Heidelberg,70,,3477-3488. |
| 60 | Paddibhatla, Indira., Gautam, Dushyant., Gutti, Ravi., (2021) , SETDB1 mutants are immune compromised with decreased AMP expression and hematopoietic defects , International Journal of Antimicrobial Agents, Elsevier,58,,21002946. |
| 59 | Gautam, Dushyant., Gutti, Ravi., Paddibhatla, Indira., (2021) , Methotrexate hinders the expression of Drosomycin induced via Toll/NF-KB pathway in both acute and chronic inflammation , International Journal of Antimicrobial Agents, Elsevier,58,,21002934. |
| 58 | Kovuru, Narasaiah., Raghuwanshi, Sanjeev., Sharma, Durga Shankar., Dahariya, Swati., Pallepati, Adithya., Gutti, Ravi Kumar., (2020) , Endoplasmic reticulum stress induced apoptosis and caspase activation is mediated through mitochondria during megakaryocyte differentiation , Mitochondrion, Elsevier,50,,115-120. |
| 57 | Pelzl, Lisann., Sahu, Itishri., Ma, Ke., Heinzmann, David., Bhuyan, Abdulla Al Mamun., Al-Maghout, Tamer., Sukkar, Basma., Sharma, Yamini., Marini, Irene., Rigoni, Flaviana., (2020) , Beta-glycerophosphate-induced ORAI1 expression and store operated Ca2+ entry in megakaryocytes , Scientific reports, Nature Publishing Group UK London,10,1,1728. |
| 56 | Raghuwanshi, Sanjeev., Dahariya, Swati., Sharma, Durga Shankar., Kovuru, Narasaiah., Sahu, Itishri., Gutti, Ravi Kumar., (2020) , RUNX1 and TGF‐β signaling cross talk regulates Ca2+ ion channels expression and activity during megakaryocyte development , The FEBS Journal, ,287,24,5411-5438. |
| 55 | Raghuwanshi, Sanjeev., Agarwal, Rashi., Raval, Ritu., Gutti, Ravi Kumar., (2020) , Chitosan nanoparticles and their applications in drug delivery, hemostasis, and stem cell research , Functional Bionanomaterials: From Biomolecules to Nanoparticles, Springer International Publishing,,,129-143. |
| 54 | Raghuwanshi, Sanjeev., Dahariya, Swati., Musvi, Syed Shahid., Gutti, Usha., Kandi, Ravinder., Undi, Ram Babu., Sahu, Itishri., Gautam, Dushyant Kumar., Paddibhatla, Indira., Gutti, Ravi Kumar., (2019) , MicroRNA function in megakaryocytes , Platelets, Taylor & Francis,30,7,809-816. |
| 53 | Raghuwanshi, Sanjeev., Sharma, Durga Shankar., Kandi, Ravinder., Kovuru, Narasaiah., Dahariya, Swati., Musvi, Syed Shahid., Venkatakrishnan, Anuradha Chimata., Pallepati, Adithya., Gutti, Ravi Kumar., (2019) , Pituitary adenylate cyclase-activating polypeptide (PACAP): Differential effects on neonatal vs adult megakaryocytopoiesis , Thrombosis Research, Elsevier,175,,59-60. |
| 52 | Pelzl, L., Sahu, I., Heinzmann, D., Bhuyan, AAM., Marini, I., Rigoni, F., Artunc, F., Sukkar, B., Cao, H., Gutti, R., (2019) , Phosphate-induced ORAI1 Expression and Store Operated Ca2+ Entry in Megakaryocytes , Hämostaseologie, Georg Thieme Verlag KG,39,S 01,SY05-2-AB. |
| 51 | Kummari, Githavani., Gutti, Ravi K., Kalle, Arunasree M., (2019) , HDAC6 promotes PMA-induced megakaryocyte differentiation of K562 cells by regulating ROS levels via NOX4 and repressing Glycophorin A , bioRxiv, Cold Spring Harbor Laboratory,,,578096. |
| 50 | Kovuru, Narasaiah., Raghuwanshi, Sanjeev., Gutti, Ravi Kumar., (2019) , Exosome mediated differentiation of megakaryocytes: a study on TLR mediated effects , Journal of Thrombosis and Thrombolysis, Springer US,48,,171-173. |
| 49 | Dahariya, Swati., Paddibhatla, Indira., Kumar, Santosh., Raghuwanshi, Sanjeev., Pallepati, Adithya., Gutti, Ravi Kumar., (2019) , Long non-coding RNA: Classification, biogenesis and functions in blood cells , Molecular immunology, Pergamon,112,,82-92. |
| 48 | Pallepati, Adithya., Mitra, Chanchal K., Gutti, Ravi Kumar., (2019) , Kinetic Modeling of Sodium-glucose Co-transport , Proceedings of the 6th International Conference on Bioinformatics Research and Applications, ,,,135-140. |
| 47 | Raghuwanshi, Sanjeev., Gutti, Usha., Kandi, Ravinder., Gutti, Ravi Kumar., (2018) , MicroRNA‐9 promotes cell proliferation by regulating RUNX1 expression in human megakaryocyte development , Cell Proliferation, Wiley-Blackwell,51,1,. |
| 46 | Raghuwanshi, Sanjeev., Dahariya, Swati., Kandi, Ravinder., Gutti, Usha., Undi, Ram B., Sharma, Durga Shankar., Sahu, Itishri., Kovuru, Narasaiah., Yarla, Nagendra Sastry., Saladi, Raja GV., (2018) , Epigenetic mechanisms: role in hematopoietic stem cell lineage commitment and differentiation , Current Drug Targets, Bentham Science Publishers,19,14,1683-1695. |
| 45 | Sahu, Itishri., Hebalkar, Rucha., Kar, Sonika., Sreevidya, TS., Gutti, Usha., Gutti, Ravi Kumar., (2018) , Systems biology approach to study the role of miRNA in promoter targeting during megakaryopoiesis , Experimental Cell Research, Academic Press,366,2,192-198. |
| 44 | Bansal, Priyanka., Dahate, Priyanka., Raghuwanshi, Sanjeev., Sharma, Durga S., Kovuru, Narasaiah., Gutti, Usha., Yarla, Nagendra Sastry., Gutti, RavI Kumar., (2018) , Current updates on role of lipids in hematopoiesis , Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious Disorders), Bentham Science Publishers,18,3,192-198. |
| 43 | Gutti, Usha., Komati, Jaswant Kumar., Kotipalli, Aneesh., Saladi, Raja Gopal Venakata., Gutti, Ravi Kumar., (2018) , Justicia adhatoda induces megakaryocyte differentiation through mitochondrial ROS generation , Phytomedicine, Urban & Fischer,43,,135-139. |
| 42 | Usha Gutti, Usha Gutti., Komati, JK., Aneesh Kotipalli, Aneesh Kotipalli., Saladi, RGV., Gutti, RK., (2018) , Justicia adhatoda induces megakaryocyte differentiation through mitochondrial ROS generation. , , ,,,. |
| 41 | Undi, Ram Babu., Gutti, Usha., Gutti, Ravi Kumar., (2017) , LiCl regulates mitochondrial biogenesis during megakaryocyte development , Journal of Trace Elements in Medicine and Biology, Urban & Fischer,39,,193-201. |
| 40 | Sahu, Itishri., Pelzl, Lisann., Sukkar, Basma., Fakhri, Hajar., al‐Maghout, Tamer., Cao, Hang., Hauser, Stefan., Gutti, Ravi., Gawaz, Meinrad., Lang, Florian., (2017) , NFAT5‐sensitive Orai1 expression and store‐operated Ca2+ entry in megakaryocytes , The FASEB Journal, Federation of American Societies for Experimental Biology,31,8,3439-3448. |
| 39 | Al-Maghout, Tamer., Pelzl, Lisann., Sahu, Itishri., Sukkar, Basma., Hosseinzadeh, Zohreh., Gutti, Ravi., Laufer, Stefan., Voelkl, Jakob., Pieske, Burkert., Gawaz, Meinrad., (2017) , P38 Kinase, SGK1 and NF-κB Dependent Up-Regulation of Na+/Ca2+ Exchanger Expression and Activity Following TGFß1 Treatment of Megakaryocytes , Cellular Physiology and Biochemistry, S. Karger AG,42,6,2169-2181. |
| 38 | Undi, Ram Babu., Gutti, Usha., Sahu, Itishri., Sarvothaman, Shilpa., Pasupuleti, Satya Ratan., Kandi, Ravinder., Gutti, Ravi Kumar., (2016) , Wnt signaling: role in regulation of haematopoiesis , Indian Journal of Hematology and Blood Transfusion, Springer India,32,,123-134. |
| 37 | Undi, Ram Babu., Sarvothaman, Shilpa., Narasaiah, Kovuru., Gutti, Usha., Gutti, Ravi Kumar., (2016) , Toll-like receptor 2 signalling: Significance in megakaryocyte development through wnt signalling cross-talk and cytokine induction , Cytokine, Academic Press,83,,245-249. |
| 36 | Gutti, Usha., Pasupuleti, Satya Ratan., Sahu, Itishri., Kotipalli, Aneesh., Undi, Ram Babu., Kandi, Ravinder., Saladi, Raja Gopal Venakata., Gutti, Ravi Kumar., (2016) , Erythropoietin and thrombopoietin mimetics: Natural alternatives to erythrocyte and platelet disorders , Critical reviews in oncology/hematology, Elsevier,108,,175-186. |
| 35 | Gupta, Aparna Dutta., Senthilkumaran, Balasubramanian., Jagota, Anita., Yenugu, Suresh., Manavathi, Bramanandam., Gutti, Ravi Kumar., Kurukuti, Sreenivasulu., (2016) , Editorial for IC-FCEN 2014. , General and Comparative Endocrinology, ,239,,1-3. |
| 34 | Aneesh Kotipalli, Ravikumar Gutti, Chanchal K Mitra., (2016) , Dynamics of miRNA biogenesis and nuclear transport , Journal of Integrative Bioinformatics, de Gruyter,13,305,. |
| 33 | Karnati, Hanuma Kumar., Pasupuleti, Satya Ratan., Kandi, Ravinder., Undi, Ram Babu., Sahu, Itishri., Kannaki, TR., Subbiah, Madhuri., Gutti, Ravi Kumar., (2015) , TLR-4 signalling pathway: MyD88 independent pathway up-regulation in chicken breeds upon LPS treatment , Veterinary research communications, Springer Netherlands,39,,73-78. |
| 32 | Kandi, Ravinder., Gutti, Usha., Undi, Rambabu., Sahu, Itishri., Gutti, Ravi Kumar., (2015) , Understanding thrombocytopenia: physiological role of microRNA in survival of neonatal megakaryocytes , Journal of thrombosis and thrombolysis, Springer US,40,,310-316. |
| 31 | Sarvothaman, Shilpa., Undi, Ram Babu., Pasupuleti, Satya Ratan., Gutti, Usha., Gutti, Ravi Kumar., (2015) , Apoptosis: role in myeloid cell development , Blood research, Korean Society of Hematology,50,2,73. |
| 30 | Karnati, Hanuma Kumar., Panigrahi, Manas Kumar., Gutti, Ravi Kumar., Greig, Nigel H., Tamargo, Ian A., (2015) , miRNAs: key players in neurodegenerative disorders and epilepsy , Journal of Alzheimer\'s Disease, IOS Press,48,3,563-580. |
| 29 | Karnati, Hanuma Kumar., Raghuwanshi, Sanjeev., Sarvothaman, Shilpa., Gutti, Usha., Saladi, Raja Gopal Venakata., Komati, Jaswant Kumar., Tummala, Prathibha Reddy., Gutti, Ravi Kumar., (2015) , microRNAs: key players in hematopoiesis , microRNA: Basic Science: From Molecular Biology to Clinical Practice, Springer International Publishing,,,171-211. |
| 28 | Kandi, Ravinder., Undi, Rambabu., Gutti, Ravi Kumar., (2014) , MiR-125b regulates cell proliferation and survival in neonatal megakaryocytes , Annals of hematology, Springer Berlin Heidelberg,93,,1065-1066. |
| 27 | Ferrer‐Marin, Francisca., Gutti, Ravi., Liu, Z‐J., Sola‐Visner, Martha., (2014) , MiR‐9 contributes to the developmental differences in CXCR‐4 expression in human megakaryocytes , Journal of Thrombosis and Haemostasis, Elsevier,12,2,282-285. |
| 26 | Karnati, Hanuma Kumar., Yalagala, Ravi Shekar., Undi, Rambabu., Pasupuleti, Satya Ratan., Gutti, Ravi Kumar., (2014) , Therapeutic potential of siRNA and DNAzymes in cancer , Tumor biology, Springer Netherlands,35,,9505-9521. |
| 25 | Sahu I, Mishra S, Babu Undi R, Kandi R, Gutti U, Kumar Gutti R., (2014) , Sequence and structural difference favors a distinct preference of Wnt3a binding with co-receptor LRP6. , J Biomol Struct Dyn, Taylor Francis Online,,25,1-33.. |
| 24 | Kandi, Ravinder., Gutti, Usha., Saladi, RG., Gutti, Ravi Kumar., (2014) , MiR-125b and miR-99a encoded on chromosome 21 co-regulate vincristine resistance in childhood acute megakaryoblastic leukemia. , Hematology/Oncology and Stem Cell Therapy, ,8,2,95-97. |
| 23 | Undi, Ram Babu., Kandi, Ravinder., Gutti, Ravi Kumar., (2013) , MicroRNAs as haematopoiesis regulators , Advances in hematology, Hindawi,2013,,. |
| 22 | Tsai-Morris, Chon-Hwa., Sato, Hisashi., Gutti, Ravi., Dufau, Maria L., (2012) , Role of gonadotropin regulated testicular RNA helicase (GRTH/Ddx25) on polysomal associated mRNAs in mouse testis , PloS one, Public Library of Science,7,3,e32470. |
| 21 | Liu, Zhi-Jian., Italiano Jr, Joseph., Ferrer-Marin, Francisca., Gutti, Ravi., Bailey, Matthew., Poterjoy, Brandon., Rimsza, Lisa., Sola-Visner, Martha., (2011) , Developmental differences in megakaryocytopoiesis are associated with up-regulated TPO signaling through mTOR and elevated GATA-1 levels in neonatal megakaryocytes , Blood, The Journal of the American Society of Hematology, American Society of Hematology Washington, DC,117,15,4106-4117. |
| 20 | Dufau, Maria L., Sato, Hisashi., Gutti, Ravi., Tsai-Morris, Chon-Hwa., (2011) , Gonadotropin-regulated testicular helicase (GRTH/DDX25): a master post-transcriptional regulator of spermatogenesis , Hormonal and Genetic Basis of Sexual Differentiation Disorders and Hot Topics in Endocrinology: Proceedings of the 2nd World Conference, Springer New York,,,23-29. |
| 19 | Tsai‐Morris, Chon‐Hwa., Sheng, Yi., Gutti, Ravi K., Tang, Pei‐Zhong., Dufau, Maria L., (2010) , Gonadotropin‐regulated testicular RNA helicase (GRTH/DDX25): a multifunctional protein essential for spermatogenesis , Journal of andrology, Blackwell Publishing Ltd Oxford, UK,31,1,45-52. |
| 18 | Ferrer-Marin, Francisca., Liu, Zhi-Jian., Gutti, Ravi., Sola-Visner, Martha., (2010) , Neonatal thrombocytopenia and megakaryocytopoiesis , Seminars in hematology, WB Saunders,47,3,281-288. |
| 17 | Tsai‐Morris, Chon‐Hwa., Sheng, Yi., Gutti, Ravi., Li, Jie., Pickel, James., Dufau, Maria L., (2010) , Gonadotropin‐regulated testicular RNA helicase (GRTH/DDX25) gene: Cell‐specific expression and transcriptional regulation by androgen in transgenic mouse testis , Journal of cellular biochemistry, Wiley Subscription Services, Inc., A Wiley Company,109,6,1142-1147. |
| 16 | Sallmon, H., Gutti, RK., Ferrer-Marin, F., Liu, ZJ., Sola-Visner, MC., (2010) , Increasing platelets without transfusion: is it time to introduce novel thrombopoietic agents in neonatal care? , Journal of Perinatology, Nature Publishing Group,30,12,765-769. |
| 15 | Ferrer-Marin, Francisca., Gutti, Ravi K., Liu, Zhi-Jian., Italiano, Joseph., Hu, Zhongbo., Slayton, William., Sola-Visner, Martha., (2010) , Neonatal megakaryocytes do not mature normally in the absence of Thrombopoietin in vivo: potential role of developmental differences in CXCR4 expression , Blood, Content Repository Only!,116,21,88. |
| 14 | Gutti, Ravi K., Sallmon, Hannes., Liu, Zhi-Jian., Ferrer-Marin, Francisca., Cantor, Alan., Bailey, Matthew., Sola-Visner, Martha., (2010) , Developmental Differences In the Let-7b/IMP-1/IGF-II Axis contribute to the High Proliferative Rate of Neonatal Megakaryocyte Progenitors. , Blood, Content Repository Only!,116,21,1598. |
| 13 | Gutti, Ravi K., (2010) , Introduction to microRNA , , ,,,. |
| 12 | Gutti, Ravi K., Tsai-Morris, Chon-Hwa., Dufau, Maria L., (2008) , Gonadotropin-regulated testicular helicase (DDX25), an essential regulator of spermatogenesis, prevents testicular germ cell apoptosis , Journal of Biological Chemistry, Elsevier,283,25,17055-17064. |
| 11 | Gutti, Ravi Kumar., Tsai‐Morris, Chon‐Hwa., Dufau, Maria L., (2008) , Gonadotropin‐Regulated Testicular Helicase (GRTH/Ddx25): A Negative Regulator of Apoptosis in Male Germ Cells , , Federation of American Societies for Experimental Biology,,,. |
| 10 | Tsai-Morris, Chon-Hwa., Koh, Eitetsu., Sheng, Yi., Maeda, Yuji., Gutti, Ravi., Namiki, Mikio., Dufau, Maria L., (2007) , Polymorphism of the GRTH/DDX25 gene in normal and infertile Japanese men: a missense mutation associated with loss of GRTH phosphorylation , Molecular human reproduction, Oxford University Press,13,12,887-892. |
| 9 | Tsai-Morris, Chon-Hwa., Koh, Eitetsu., Sheng, Yi., Maeda, Yuji., Gutti, Ravi., Namiki, Mikio., Dufau, Maria L., (2007) , Revised MHR 07-204 Polymorphism of the GRTH/DDX25 gene in normal and infertile Japanese men: a missense mutation associated with loss of GRTH phosphorylation. , , ,,,. |
| 8 | Sheng, Yi., Tsai-Morris, Chon-Hwa., Gutti, Ravi., Maeda, Yuji., Dufau, Maria L., (2006) , Gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) is a transport protein involved in gene-specific mRNA export and protein translation during spermatogenesis , Journal of Biological Chemistry, Elsevier,281,46,35048-35056. |
| 7 | Bhalla, KN., George, P., Gutti, R., Bali, P., Tao, J., Guo, F., Sigua, C., Li, Y., Cohen, P., Atadja, P., (2004) , A combination of histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC and AML cells with constitutively active mutant FLT-3 tyrosine kinase , Journal of Clinical Oncology, American Society of Clinical Oncology,22,14_suppl,6541-6541. |
| 6 | Gutti, Ravi., George, Prince., Bali, Purva., Tao, Jianguo., Guo, Fei., Sigua, Celia., Li, Yunqing., Moscinski, Lynn., Atadja, Peter., Bhalla, Kapil N., (2004) , A combination of histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC and AML cells with constitutively active mutant FLT-3 tyrosine kinase. , Cancer Research, American Association for Cancer Research,64,7_Supplement,699-699. |
| 5 | Guo, Fei., Sigua, Celia., Bali, Purva., George, Prince., Gutti, Ravi., Li, Yunqing., Bhalla, Kapil N., (2004) , Mechanistic link between hsp70 overexpression upregulation of STAT5 and Bcl-xL and resistance to cytarabine, etoposide or Apo-2L/TRAIL-induced apoptosis in Bcr-Abl expressing acute leukemia cells , Cancer Research, American Association for Cancer Research,64,7_Supplement,135-136. |
| 4 | George, P., Bali, P., Jianguo, T., Vishvanath, A., Guo, F., Sigua, C., Gutti, R., Li, YQ., Moscinski, L., Cohen, P., (2003) , Treatment with heat shock protein-90 inhibitor 17-allyl-demethoxy-geldanamycin (17-AAG) induces proteasomal degradation of mutant FLT-3 and enhances PKC412-mediated apoptosis of human AML cells with constitutively active mutant FLT-3 tyrosine kinase. , Blood, AMER SOC HEMATOLOGY 1900 M STREET. NW SUITE 200, WASHINGTON, DC 20036 USA,102,11,598A-598A. |
| 3 | Li, YQ., Guo, F., Sigua, C., Tao, JG., Bali, P., Vishvanath, A., Gutti, R., George, P., Moscinski, L., Atadja, P., (2003) , Combined treatment with histone deacetylase inhibitor LAQ824 and Apo-2L/TRAIL: Mechanistic basis of superior activity against human acute leukemia and CML-BC cells. , Blood, AMER SOC HEMATOLOGY 1900 M STREET. NW SUITE 200, WASHINGTON, DC 20036 USA,102,11,595A-595A. |
| 2 | Bali, P., George, P., Tao, JG., Guo, F., Sigua, C., Vishvanath, A., Gutti, R., Li, YQ., Moscinski, L., Cohen, P., (2003) , A combination of historic deacetylase inhibitor LAQ824 and the FLT-3 kinase inhibitor PKC412 is highly active against human AML cells with constitutively active mutant FLT-3 tyrosine kinase. , Blood, AMER SOC HEMATOLOGY 1900 M STREET. NW SUITE 200, WASHINGTON, DC 20036 USA,102,11,96A-97A. |
| 1 | Sahu, Itishri., Pelzl, Lisann., Sukkar, Basma., Fakhri, Hajar., al-Maghout, Tamer., Cao, Hang., Hauser, Stefan., Gutti, Ravi., Gawaz, Meinrad., Lang, Florian., (1977) , Dna damage inhibitor , , ,,,. |
| Patent No/Application No | Patent Title | Authors | Applied Year | Granting Year |
|---|---|---|---|---|
| 201641007591 | miRNA mediated Mitochondrial Biogenesis | Ram Babu Undi, Ravi Kumar Gutti | 2016 | IN-PROCESS |
| Title | Year | Duration | Amount(In Lakhs) | PI/I |
|---|---|---|---|---|
| Natural alternatives to neonatal thrombocytopenia and other platelet developmental disorders | 2024 | 3 | 6230080 | PI |
| Cannabinoid Receptor Signaling in Megakaryocyte Development: Significance in Neuro-immune Regulation | 2023 | 3 | 4250000 | Ravi Kumar Gutti |
| Role of Long non-coding RNA in hiPSC derived Megakaryocytes: A lncRNA, miRNA and cell cycle regulators interaction study | 2021 | 3 | 5000000 | Ravi Kumar Gutti |
| Creation of a genetic resource of ........fruit ripening and phosphate starvation response | 2019 | 3 | 200000000000 | PI |
| Understanding genetic diversity ..... to low phosphate in tomato | 2019 | 3 | 350000000000 | PI |
| Long non-coding RNA Regulation: Role in megakaryocyte development | 2019 | 3 | 1800000 | PI |
| From small to big: microRNAs as new players in developmental megakaryocytopoiesis | 2019 | 3 | 4660000 | PI |
| Toll-like Receptor Signalling: Significance in Megakaryocyte Development and Platelet Production | 2019 | 3 | 4620000 | PI |
| SETDB1 in hematopoiesis and hematopoietic tumors: Target genes and their regulation | 2018 | 3 | 3000000 | Mentor |
| Molecular regulation of the differences between neonatal and adult megakaryocytopoiesis leading to bleeding disorders | 2014 | 3 | 2500000 | PI |
| Potential signaling pathways in molecular regulation of different developmental stages of human megakaryocytes | 2013 | 3 | 5290000 | PI |
| miR-9/Runx1 mediates developmental regulation of distinct megakaryocytopoiesis | 2013 | 3 | 3325000 | PI |
| Identification and characterization of novel microRNA of clinical importance from neonatal and adult derived megakaryocytes | 2012 | 3 | 960000 | PI |
| Role of Toll-like Receptor Signaling Mediated Disease Resistance in Indian Poultry | 2012 | 3 | 2725000 | PI |
| Potential role of miR-9 regulation in CXCR-4 expression at different developmental stages of human megakaryocytes | 2012 | 4 | 4181000 | PI |
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