Faculty Details

Faculty Details

  • Name: Dr. Seema Mishra
  • Mail: smsluohyd.ernet.in
  • Contact:
  • Area Of Research:Our field of research lies in Computational and Systems Biology. We use these futuristic approaches in analyzing big data. Specifically, our aim is to identify and establish interrelationships between coding (mRNA) and long non-coding (lncRNA) genes playing a key role in pan-cancer development and progression. Their roles in pan-cancer drug resistance and sensitivity are also being analyzed to understand the molecular mechanisms and propose key regulatory paradigms. We also use molecular dynamics simulations to understand structural basis of drug-protein target interactions in cancer, and putting forward inside views of the domain movements and essential conformational changes.
No Records Available

Students/Projects Trainees

Name Joined As Mail Contact
Mr. Kesaban Ph.D --- ---
Mr. Santosh Kumar Ph.D --- ---
Ms. K. Praveena Ph.D --- ---
Ms. Euphinia Tiberius Ph.D --- ---
Mr. Rohan Bhandari IMSc-Ph.D --- ---

Former Students/Projects Trainees

Name Joined As Working
Dr. A. Saleembhasha Ph.D NIH, USA for Post-doc
Ms. Soumi Mukherjee M.Sc Purdue University for Ph.D
Mr. Sagara N. S. Gurusinghe M.Sc Hebrew University of Jerusalem, Israel for his Ph.D
Ms. Rituparna Bhattacharjee M.Sc Otto-von-Guericke-University Magdeburg for her Ph.D
Ms. Amita Pal M.Sc Pursuing Ph.D at UoH
Mr. S. Niranjan M.Sc Pursuing Ph.D at UoH
Mr. Pankaj Kumar Chauhan IMSc NCBS for his PhD
8 A. Saleembhasha and Seema Mishra (2019) , Long non-coding RNAs as pan-cancer master gene regulators of associated protein-coding genes: a systems biology approach. , PeerJ, ,,7:e6388,.
7 KRD Sagara NS Gurusinghe, A Mishra and Seema Mishra (2018) , Glucose-regulated protein 78 substrate-binding domain alters its conformation upon EGCG inhibitor binding to nucleotide-binding domain: Molecular dynamics studies. , Scientific Reports, ,,8:5487,.
6 Saleembhasha A, Mishra S. (2017) , Novel molecules lncRNAs, tRFs and circRNAs deciphered from Next Generation Sequencing/RNA Sequencing: computational databases and tools. , Briefings in Functional Genomics, Oxford University Press,1-11,,.
5 Seema Mishra, D.S. Negi and Seyed E. Hasnain (2016) , DNA Fingerprinting: Principles and Applications. , Text Book of Biochemistry, Biotechnology, Allied and Molecular Medicine, Prentice Hall of India ISBN: 978-81-203-5125-7.,,,834-840.
4 Seema Mishra* and Syed Asad Rahman (2016) , Bioinformatics, Genomics, Proteomics and Metabolomics in Biomedical Research. , Text Book of Biochemistry, Biotechnology, Allied and Molecular Medicine, Prentice Hall of India ISBN: 978-81-203-5125-7,,,1549-1558.
3 Khushboo Irshad, Saroj Kant Mohapatra, Chitrangda Srivastava, Harshit Garg, Seema Mishra, Bhawana Dikshit, Chitra Sarkar, Deepak Gupta, Poodipedi Sarat Chandra, Parthaprasad Chattopadhyay, Subrata Sinha, Kunzang Chosdol. (2015) , A Combined Gene Signature of Hypoxia and Notch Pathway in Human Glioblastoma and Its Prognostic Relevance. , PLoS One, ,10(3): e0118201,,.
2 Rituparna Bhattacharjee, Arpita Devi and Seema Mishra (2015) , Molecular docking and molecular dynamics studies reveal structural basis and selectivity of inhibitors EGCG and OSU-03012 towards Glucose Regulated Protein-78 (GRP78) overexpressed in Glioblastoma. , Journal of Molecular Modeling , Springer,21:272,,.
1 Seema Mishra and Subrata Sinha (2014) , Immunoinformatics, molecular modeling and cancer vaccines. , Methods in Molecular Biology, Humana Press/Springer,1184,,513-521.