Faculty Details

Faculty Details

  • Name: Dr. Vijay Morampudi
  • Mail: vmorampudivgmail.com
  • Contact: 7702849094
  • Area Of Research:Host-Commensal-Pathogenic Interactions, Intestinal Inflammation, Mucosal Immunology and Cell-signalling pathways.

EDUCATION:

(2011)       PhD in Biomedical and Pharmaceutical Sciences, Université Libre de Bruxelles, Brussels, Belgium.


(2006)       M.S. in Medical and Pharmaceutical Research, Vrije Universiteit Brussel, Brussels, Belgium (Distinction).


(2001)       Bachelor in Pharmacy, Osmania University, Hyderabad, Telangana, India.



EXPERIENCE: 

·    [Acematiks, Inc., QC, CANADA] [Academic tutor and Writer] for PhD professionals (2018-2019).

·    [Engene Inc, QC, CANADA] [Scientist/Biology Lead, Immunology]: Studying the therapeutic efficacy of an immunomodulatory protein in a mouse bladder cancer (2017- 2108).

·    [University of British Columbia (UBC), Faculty of Medicine, BC, CANADA] [Post-doctoral Fellow]: Defining the role of goblet cell secreting factors Resistin like molecule beta (RELM-beta) and Mucin 2 (Muc2) in a mouse model of intestinal inflammation (2011- 2016).

·    [Université Libre de Bruxelles (ULB), Belgium] [PhD student]: Studying the modulation of innate immune responses in intestinal epithelial cells by Toxoplasma gondii and its correlation with parasite virulence (2006-2011).


ACADEMIC AWARDS and HONOURS

·      Michael Smith Foundation Health Research Fellowship (MSFHR), Canada, PDF fellowship (2013 to 2016).


·      Child and Family Research Fellowship (CFRI), Canada (2012).


·      3R Research Foundation, Switzerland, PhD Scholarship (2008 to 2010).


·      Van Buuren Scholarship, Belgium for 3 months.


·      Pasteur Institute of Brussels Scholarship, Belgium (2007).


·      Belgium Immunological Society Travel Award, Belgium (2009).


·      Invited to Chair UBC organized graduate seminar day, Vancouver, Canada (2012 & 2015).


·      Invited poster judge on UBC organized Experimental Medicine day, Vancouver, Canada (2012 to 2015).


·      Invited speaker in International Congress of Mucosal Immunology, Vancouver, Canada (2013).


LICENCES AND CERTIFICATIONS

 

·      Licensed Pharmacist in India

·      National Institute of Health (NIH) certificate in Clinical Research Training course (2016)

·      Biological safety

·      Canadian Council of Animal Care (CCAC)

·      Rodent Biology and Husbandry

·      Rodent Anesthesia and Surgery

·      Project management

·      Scientific Writing

·      Professional and Business Effectiveness.

  



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16 Allaire, Joannie M., Morampudi, Vijay., Crowley, Shauna M., Stahl, Martin., Yu, Hongbing., Bhullar, Kirandeep., Knodler, Leigh A., Bressler, Brian., Jacobson, Kevan., Vallance, Bruce A., (2018) , Frontline defenders: goblet cell mediators dictate host-microbe interactions in the intestinal tract during health and disease , American Journal of Physiology-Gastrointestinal and Liver Physiology, American Physiological Society Bethesda, MD,314,3,G360-G377.
15 Patankar, Jay V., Wong, Chi K., Morampudi, Vijay., Gibson, William T., Vallance, Bruce., Ioannou, George N., Hayden, Michael R., (2018) , Genetic ablation of Cyp8b1 preserves host metabolic function by repressing steatohepatitis and altering gut microbiota composition , American Journal of Physiology-Endocrinology and Metabolism, American Physiological Society Bethesda, MD,314,5,E418-E432.
14 Sham, Ho Pan., Bazett, Mark., Bosiljcic, Momir., Yang, Hyungjun., Luk, Beryl., Law, Hong T., Morampudi, Vijay., Yu, Hong B., Pankovich, Jim., Sutcliffe, Simon., (2018) , Immune stimulation using a gut microbe-based immunotherapy reduces disease pathology and improves barrier function in ulcerative colitis , Frontiers in immunology, Frontiers,9,,2211.
13 Morampudi, Vijay., Graef, Franziska A., Stahl, Martin., Dalwadi, Udit., Conlin, Victoria S., Huang, Tina., Vallance, Bruce A., Hong, B Yu., Jacobson, Kevan., (2017) , Tricellular tight junction protein tricellulin is targeted by the enteropathogenic Escherichia coli effector EspG1, leading to epithelial barrier disruption , Infection and Immunity, American Society for Microbiology Journals,85,1,.
12 Chung, H., Vilaysane, A., Lau, A., Stahl, M., Morampudi, V., Bondzi-Simpson, A., Platnich, JM., Bracey, NA., French, MC., Beck, PL., (2016) , NLRP3 regulates a non-canonical platform for caspase-8 activation during epithelial cell apoptosis , Cell Death & Differentiation, Nature Publishing Group,23,8,1331-1346.
11 Morampudi, V., Dalwadi, U., Bhinder, G., Sham, HP., Gill, SK., Chan, J., Bergstrom, KSB., Huang, T., Ma, C., Jacobson, K., (2016) , The goblet cell-derived mediator RELM-beta drives spontaneous colitis in Muc2-deficient mice by promoting commensal microbial dysbiosis , Mucosal immunology, Nature Publishing Group,9,5,1218-1233.
10 Bergstrom, Kirk SB., Morampudi, Vijay., Chan, Justin M., Bhinder, Ganive., Lau, Jennifer., Yang, Hyungjun., Ma, Caixia., Huang, Tina., Ryz, Natasha., Sham, Ho Pan., (2015) , Goblet cell derived RELM-_ recruits CD4+ T cells during infectious colitis to promote protective intestinal epithelial cell proliferation , PLoS Pathog, Public Library of Science,11,8,e1005108.
9 Wu, Xiujuan., Conlin, Victoria S., Morampudi, Vijay., Ryz, Natasha R., Nasser, Yasmin., Bhinder, Ganive., Bergstrom, Kirk S., Hong, B Yu., Waterhouse, Chris CM., Buchan, Allison MJ., (2015) , Vasoactive intestinal polypeptide promotes intestinal barrier homeostasis and protection against colitis in mice , PloS one, Public Library of Science,10,5,e0125225.
8 Morampudi, Vijay., Conlin, Victoria Susan., Dalwadi, Udit., Wu, Xiujuan., Marshall, Kelsey C., Nguyen, Christine., Vallance, Bruce A., Jacobson, Kevan., (2015) , Vasoactive intestinal peptide prevents PKC_-induced intestinal epithelial barrier disruption during EPEC infection , American Journal of Physiology-Gastrointestinal and Liver Physiology, American Physiological Society Bethesda, MD,308,5,G389-G402.
7 Bhinder, Ganive., Stahl, Martin., Sham, Ho Pan., Crowley, Shauna M., Morampudi, Vijay., Dalwadi, Udit., Ma, Caixia., Jacobson, Kevan., Vallance, Bruce A., (2014) , Intestinal epithelium-specific MyD88 signaling impacts host susceptibility to infectious colitis by promoting protective goblet cell and antimicrobial responses , Infection and immunity, American Society for Microbiology Journals,82,9,3753-3763.
6 Morampudi, Vijay., Bhinder, Ganive., Wu, Xiujuan., Dai, Chuanbin., Sham, Ho Pan., Vallance, Bruce A., Jacobson, Kevan., (2014) , DNBS/TNBS colitis models: providing insights into inflammatory bowel disease and effects of dietary fat , JoVE (Journal of Visualized Experiments), ,,84,e51297.
5 Bhinder, Ganive., Sham, Ho Pan., Chan, Justin M., Morampudi, Vijay., Jacobson, Kevan., Vallance, Bruce A., (2013) , The Citrobacter rodentium mouse model: studying pathogen and host contributions to infectious colitis , JoVE (Journal of Visualized Experiments), ,,72,e50222.
4 Hekmatdoost, Azita., Wu, Xiujuan., Morampudi, Vijay., Innis, Sheila M., Jacobson, Kevan., (2013) , Dietary oils modify the host immune response and colonic tissue damage following Citrobacter rodentium infection in mice , American Journal of Physiology-Gastrointestinal and Liver Physiology, American Physiological Society Bethesda, MD,304,10,G917-G928.
3 Sham, Ho Pan., Yu, Emily Yi Shan., Gulen, Muhammet F., Bhinder, Ganive., Stahl, Martin., Chan, Justin M., Brewster, Lara., Morampudi, Vijay., Gibson, Deanna L., Hughes, Michael R., (2013) , SIGIRR, a negative regulator of TLR/IL-1R signalling promotes Microbiota dependent resistance to colonization by enteric bacterial pathogens , PLoS Pathog, Public Library of Science,9,8,e1003539.
2 Morampudi, Vijay., Braun, Michel Y., D\'Souza, Sushila., (2011) , Modulation of early _-defensin-2 production as a mechanism developed by Type I Toxoplasma gondii to evade human intestinal immunity , Infection and immunity, American Society for Microbiology Journals,79,5,2043-2050.
1 Morampudi, Vijay., De Craeye, Stephane., Le Moine, Alain., Detienne, Sophie., Braun, Michel Y., DSouza, Sushila., (2011) , Partial depletion of CD4+ CD25+ Foxp3+ T regulatory cells significantly increases morbidity during acute phase Toxoplasma gondii infection in resistant BALB/c mice , Microbes and infection, Elsevier,13,4,394-404.