Faculty
Faculty Details
Faculty Details
Dr. Kota Arun Kumar is currently an Assistant Professor at Department of
Animal Biology, School of Life Sciences. University of Hyderabad. He
graduated (PhD) from Dept of Animal Sciences, School of Life Sciences,
University of Hyderabad (1997-2002) where he studied the pathophysiology of
murine cerebral malaria. He obtained his
post doctoral training from New York University School of Medicine, USA, where
he studied the mechanism of protective immune responses against the
pre-erythocytic stages of Plasmodium
using rodent malaria model. At University of Hyderabad, his research group aims
at understanding the biology of Plasmodium liver stages and mosquito
stages by approaches of reverse genetics. His work has demonstrated that
targeting sporozoite specific genes can yield mutants that experience a block
in liver, thus preventing clinical malaria. In addition depletion of parasite specific
metabolic enzymes and proteases yielded
mutants that failed to transmit malaria.
These finding have implications for developing whole organism attenuated
vaccine for pre-erythrocytic stages and prospects for developing transmission blocking agents to eradicate
malaria.
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| 1 | (1977) , , , ,,,. |
| Title | Year | Duration | Amount(In Lakhs) | PI/I |
|---|---|---|---|---|
| Host-virus interactions - SERB | 2018 | 3 | 5500 | Dr. M. Venkataramana/ Co PI - Dr. Kota Arun Kumar, Department of Animal Biology |