Faculty Details

Faculty Details

  • Name: Dr. Anil K Pasupulati
  • Mail: pakumarsluohyd.ernet.in
  • Contact: 914023134519
  • Area Of Research:Podocytes, Hypoxia, Diabetic Nephropathy, Chronic Kidney Disease

Affiliation: Assistant Professor, Dept. Biochemistry, School of Life Sciences, UoH (from July 2014)

Education: Ph.D. Department of Biochemistry, Osmania University, Hyderabad.                                                                                                                                                                              M.Sc. Department of Biochemistry, Andhra University, Visakhapatnam.        

Post-doctoral Appointments: DST-INSPIRE Faculty, National Institute of Nutrition (2012-14); Post-doctoral Fellow, UM, Ann Arbor (2008-11); Post-doctoral Fellow, UC Irvine (2007-08).                                                                                                                                                                                                                                          

Fellowships: DHR Fellowship (2018); Wood-Whelan Fellowship by IUBMB (2014); Wellcome-DBT Early Career Fellowship (2012, not availed); DST-INSPIRE Faculty Fellowship (2012).


No Records Available

Students/Projects Trainees

Name Joined As Mail Contact
Ashish K Singh Ph.D. Candidate ashishsngh881@gmail.com ---
Sandeep Kumar Ph.D. Candidate sandeep2k9@yahoo.com 914023134519
Rajkishor Nishad Ph.D. Candidate biochemistry1520@gmail.com 914023134519
Lakshmi Prasanna Ph.D. Candidate klprasu.uohyd@gmail.com 914023134519
Syed Abrar Qadri Project Fellow syeduok@gmail.com ---
40 R Nishad, P Meshram, A Singh, GB Reddy, AK Pasupulati (2020) , Activation of Notch1 signaling in podocytes by glucose-derived AGEs contributes to proteinuria , BMJ Open Diabetes Research and Care , ,8,,e001203.
39 SKM Narasimha, P Paramita Kaur, Ramakrishna Vadrevu, AK Pasupulati (2019) , Intrinsically disordered regions mediate macromolecular assembly of the Slit diaphragm proteins associated with Nephrotic syndrome. , Molecular Simulation, ,45,,603-13.
38 AK Pasupulati, RK Menon (2019) , Growth hormone and Chronic Kidney Disease , Curr Opin Nephrol Hyperten, ,28,,10-15.
37 K Nakuluri, D Mukhi, S Mungamuri, AK Pasupulati (2019) , Stabilization of HIF1alpha by CoCl2 impairs podocyte morphology and slit-diaphragm function , J Cell Biochem, ,120,,7667-78.
36 R Nishad, D Mukhi, V Tahaseen, SK Mungamuri, AK Pasupulati (2019) , Growth hormone induces Notch1 signaling in podocytes and contributes to proteinuria in diabetic nephropathy , J Biol Chem, ASBMB,294,44,16109-16122.
35 Nakuluri K, Nishad R, Mukhi D, Kumar S, Nakka VP, Kolligundla LP, Narne P, Natuva S, Phanithi PB, Pasupulati AK (2019) , Cerebral ischemia induces TRPC6 via HIF1a/ZEB2 axis in the glomerular podocytes and contributes to proteinuria , Scientific Reports, ,,,.
34 D Mukhi, R Nishad, R Menon, AK Pasupulati (2018) , Growth hormone and metabolic homeostasis , EMJ Diabetes, ,6,,78-87.
33 S Zhang, C Lu, AK Das, AK Pasupulati, R Menon (2018) , Abrogation of GH action in Kupffer cells results in increased hepatic CD36 expression and exaggerated nonalcoholic fatty liver disease , GH , ,42-43,,74-79.
32 K Nakuluri, D Mukhi, R Nishad, M Saleem, S Mungamuri, R Menon, AK Pasupulati (2018) , Hypoxia Induces ZEB2 in Podocytes: Implications in the Pathogenesis of Proteinuria , J Cell Physiol, ,234,,6503-18.
31 T Sornapudi, R Nayak, P Guttikona, AK Pasupulati, S Kethavath, V Uppada, S Mondal, S Yellaboina, S Kurukuti (2018) , Comprehensive profiling of transcriptional networks specific for lactogenic differentiation of HC11 mammary epithelial stem-like cells. , Scientific Reports, ,,,.
30 D Mukhi, R Nishad, R Menon, AK Pasupulati (2017) , Novel actions of Growth Hormone in Podocytes: Implications for Diabetic Nephropathy , Frontiers in Medicine, ,,,.
29 R Nishad, K Nakuluri, M Motrapu, AK Pasupulati. (2017) , Epithelial–mesenchymal Transition of Glomerular Podocytes: Implications in Proteinuria , MGM J Med Sci , ,4,,1-9.
28 AK Pasupulati,, PS Chitra, GB Reddy (2016) , Advanced glycation end products mediated cellular and molecular events in the pathology of Diabetic nephropathy , Biomolecular Concepts, ,7,,293-309.
27 KNM Sandeep, R Nishad, LP Kolligundla, MA Saleem, NP Prabhu, AK Pasupulati (2016) , In Silico Structural Characterization of Podocin and Assessment of Nephrotic Syndrome-Associated Podocin Mutants , IUBMB Life, ,68,,578-88.
26 G Raghu, S Jakotia, PY Reddy, AK Pasupulati, GB Reddy (2016) , Ellagic acid inhibits non-enzymatic glycation and prevents proteinuria in diabetic rats , Food , ,7,,1574-83.
25 Anil Kumar, G Welsh, G Raghu, R Menon, M Saleem, GB Reddy (2016) , Carboxymethyl lysine induces EMT in podocytes through transcription factor ZEB2: Implications for podocyte depletion and proteinuria in diabetes mellitus , Arch Biochem Biophys, ,590,,10-19.
24 P Swathi, T Swathi, R Sahay, GB Reddy, RK Menon, Anil Kumar (2015) , Growth Hormone Induces Transforming Growth Factor-Beta-Induced Protein in Podocytes: Implications for podocyte depletion and proteinuria , J Cell Biochem, ,116,,1947-56.
23 Anil Kumar, GI Welsh, MA Saleem, RK Menon, (2014) , Molecular and Cellular Events Mediating Glomerular Podocyte Dysfunction and Depletion in Diabetes Mellitus , Frontiers in Endocrinology, ,5,,51.
22 P Muthenna, G Raghu, P Anil Kumar, MV Surekha, GB Reddy. (2014) , Effect of cinnamon and its procyanidin-B2 enriched fraction on diabetic nephropathy in rats , Chem Biol Inter, ,222,,68-76.
21 P Anil Kumar, PS Chitra, C Lu, JS Aditya, Ram Menon (2014) , Growth hormone (GH) differentially regulates NF-kB activity in preadipocytes and macrophages: Implications for GH’s role in adipose tissue homeostasis in obesity. , J Physiol Biochem, ,70,,433-40.
20 MS Reddy, G, Raghu, SS Reddy, P Anil Kumar, P Suryanarayana, GB Reddy. (2013) , Response of small heat shock proteins in diabetic rat retina , Invest Ophthalmol Vis Sci, ,54,,7674-82.
19 C Lu, P Anil Kumar, Y Fan, MA Sperling, C Lumeng, R Menon (2013) , Targeted Deletion of GHR in Macrophage Reveals Novel Osteopontin-Mediated Effects of GH on Glucose Homeostasis and Insulin Sensitivity in DIO , J Biol Chem, ,288,,15725-35.
18 P Anil Kumar, PS Chitra, GB Reddy. (2013) , Metabolic syndrome associated chronic kidney diseases: Dietary interventions , Rev Endocr Metab Disord, ,14,,273-286.
17 P Anil Kumar, GB Reddy (2013) , Nutrition and Metabolic Syndrome, Editorial , Rev Endocr Metab Disord, ,14,,217.
16 P Anil Kumar, RK Menon (2013) , New insights into growth hormone’s actions on the macrophage: implications for non-growth-related actions of growth hormone , OA Biochemistry, ,1,,15.
15 J Sun*, P Anil Kumar*, J Thimmayappa, P Goel, N Saini, C Lu, RK Menon (2011) , A Novel Non-catalytic Role for Esterase1 in Transcriptional Repression of Growth Hormone Receptor Gene Expression , Mol Endocrinol, ,5,,1351-63.
14 PA Kumar, FC Brosius, RK Menon (2011) , The Glomerular Podocyte as a Target of Growth Hormone Action: Implications for the pathogenesis of diabetic nephropathy , Current Diabetic Reviews , ,7,,50-55.
13 P Anil Kumar, C Lu, RK Menon (2011) , Novel transcriptional regulators of growth hormone receptor expression and novel targets of growth hormone action , Medicine Clinique , ,1,,36-39.
12 P Anil Kumar, K Kotlyarevska, D Prapai, R Reddy, C Lu, MS Bhojani, RK Menon (2010) , GH-dependent expression of a NAT induces ZEB2 in the glomerular podocyte: a novel action of GH with implications for the pathogenesis of diabetic nephropathy , J Biol Chem, ,285,,31148-56.
11 C Lu, PA Kumar, Y Fan, MA Sperling, RK. Menon (2010) , A novel effect of growth hormone on macrophage modulates macrophage-dependent adipocyte differentiation , Endocrinology, ,151,,2189-2199.
10 P Anil Kumar, GB Reddy (2009) , Modulation of alpha-crystallin chaperone activity: a target to prevent or delay cataract? , IUBMB Life, ,61,,485-495.
9 PA Kumar, PY Reddy, PNBS Sreenivas, GB Reddy. (2008) , Delay of Diabetic Cataract in Rats by antiglycating Potential of Cumin through Modulation of alpha-crystallin Chaperone Activity , J Nutr Biochem, ,20,,553-562.
8 P Anil Kumar, GB Reddy (2007) , Focus on Molecules: Aldose Reductase. , Exp Eye Res, ,85,,739-740.
7 P Anil Kumar, MS Kumar, GB Reddy (2007) , Effect of glycation on alpha-crystallin structure and chaperone-like function , Biochem J, ,408,,251-258.
6 GB Reddy, P Anil Kumar, MS Kumar (2006) , Chaperone like activity and hydrophobicity of alpha-crystallin , IUBMB Life, ,58,,632-644.
5 MS Moghaddam, P Anil Kumar, GB Reddy, VS Ghole (2005) , Effect of Diabecon on sugar-induced lens opacity in organ culture: mechanism of action , J Ethnopharmacol , ,97,,397-403.
4 P Anil Kumar, P Suryanarayana, PY Reddy, GB Reddy (2005) , Modulation of alpha-crystallin chaperone activity in diabetic rat lens by curcumin , Molecular Vision, ,11,,561-568.
3 P Anil Kumar, A Haseeb, P Suryanarayana, NZ Ehtesham, GB Reddy (2005) , Elevated expression of alphaA- and alphaB-crystallins in streptozotocin-induced diabetic rat , Archives Biochem Biophysica, ,444,,77-83.
2 P Suryanarayana, P Anil Kumar, M Saraswat, JM Petrash, GB Reddy. (2004) , Inhibition of aldose reductase by tannoid principles of Emblica Officinalis: Implications for the prevention of sugar cataract , Molecular Vision, ,10,,148-154.
1 MS Kumar, PY Reddy, P Anil Kumar, I Surolia, GB Reddy (2004) , Effect of dicarbonyl-induced browning on alpha-crystallin chaperone-like activity: Physiological significance and caveats of in vitro aggregation assays , Biochem J, ,379,,273-282.
Title Year Duration Amount(In Lakhs) PI/I
The role of WT1 in Obesity-related glomerulonephropathy 2020 3 80 P. Anil Kumar
Hypoxia Alters Calcium Influx in the Glomerular Podocytes: Implications in Cytoskeletal Derangement and Proteinuria 2019 3 60 P Anil Kumar
Growth hormone induces IL-17 in glomerular podocytes: Implications in the pathogenesis of diabetic nephropathy 2019 3 30 P. Anil Kumar
Silica-induced Nephrotoxicity: Implications in Uddanam Kidney Disease of Unknown Origin 2019 3 50 P. Anil Kumar
Growth hormone mediates glomerular podocyte hypertrophy: Implications in diabetic nephropathy 2018 3 18 P. Anil Kumar
Hypoxia-mediated epithelial-mesenchymal transition 2017 3 38 P. Anil Kumar
Prevention of epithelial-mesenchymal transition of podocytes by inhibition of natural antisense transcript for ZEB2: Implications for prevention of diabetic nephropathy 2016 3 51 P. Anil Kumar
Role of Growth hormone on Mammary Epithelial Carcinoma 2013 3 18 P. Anil Kumar
Novel Non-Canonical Role of Growth hormone on Glomerular Podocytes 2012 5 68 P. Anil Kumar