Faculty Details

Faculty Details

  • Name: Dr. Pankaj Singh Dholaniya
  • Mail: pankazuohyd.ac.in
  • Contact: 040-2313-4591
  • Area Of Research:
    Bioinformatics Data Science and Age-associated Neurological Disorders



EDUCATIONAL CREDENTIALS

 

Ph.D Biotechnology (2017)

Department of Biotechnology & Bioinformatics, University of Hyderabad, Hyderabad, Telangana.

 

M. Tech. Bioinformatics (2011)

University of Hyderabad, Hyderabad, Andhra Pradesh;

 

B. Tech. Biotechnology (2009)
SVBP University of Agri. & Tech., Meerut, U.P; 



FELLOWSHIPS


German Academic Exchange Service (DAAD) fellowship under NPTI program 2012

CSIR-NET Lectureship 2010

DBT-JRF 2009 and 2010

GATE 2009






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No Records Available

Students/Projects Trainees

Name Joined As Mail Contact
Baby Kumari Ph.D. baby059696@gmail.com ---
Neha Ph.D. nehaskumar101@gmail.com ---
Ahmad Ph.D. ahmadmailbook@gmail.com ---
Samreen Project Student (M.Tech., Bioinformatics) samreen9528@gmail.com ---
Mukulika Mandal Project Student (M.Tech., Bioinformatics) muku2411@gmail.com ---
Zainul Project Student (M.Sc., Bioitechnology) mdzainulali@gmail.com ---

Former Students/Projects Trainees

Name Joined As Working
Kushagra Project Student (M.Tech., Bioinformatics) Ph.D., CDRI Lucknow
Vikram Teja Naik Project Student (M.Tech., Bioinformatics)
Swarna Kundu Project Student (M.Tech., Bioinformatics) Healthcare Analyst, Apollo Health
Itishree Jali Project Student (M.Tech., Bioinformatics) Ph.D., NIAB, Hyderabad
Aishwarya Project Student (M.Sc., Bioitechnology) Ph.D., CCMB, Hyderabad
Manish Project Student (I.M.S., Systems Biology)
Neha Project Student (M.Sc., Bioitechnology) Continuing Ph.D. with same group
9 Kumari, Baby., Mandal, Mukulika., Dholaniya, Pankaj Singh., (2020) , Analysis of multiple transcriptome data to determine age-associated genes for the progression of Parkinson's disease , Meta Gene, Elsevier,25,9,.
8 Gupta, Prateek,. Dholaniya, Pankaj Singh., Devulapalli, Sameera,. Tawari, Nilesh Ramesh,. Yellamaraju, Sreelakshmi,. Sharma, Rameshwar,. (2020) , Reanalysis of Genome Sequences of tomato accessions and its wild relatives: Development of tomato genomic variation (TGV) database integrating SNPs and INDELs polymorphisms , Bioinformatics, ,,,.
7 Kakade, Aishwarya., Kumari, Baby., Dholaniya, Pankaj Singh., (2018) , Feature selection using logistic regression in case–control DNA methylation data of Parkinson\'s disease: A comparative study , Journal of theoretical biology, Academic Press,457,,14-18.
6 Bollimpelli, V Satish., Dholaniya, Pankaj S., Kondapi, Anand K., (2017) , Topoisomerase iiβ and its role in different biological contexts , Archives of biochemistry and biophysics, Academic Press,633,,78-84.
5 Gupta, K Preeti., Dholaniya, Pankaj Singh., Chekuri, Anil., Kondapi, Anand K., (2015) , Analysis of gene expression during aging of CGNs in culture: implication of SLIT2 and NPY in senescence , Age, Springer,37,3,62.
4 Dholaniya, Pankaj Singh., Ghosh, Soumitra., Surampudi, Bapi Raju., Kondapi, Anand K., (2015) , A knowledge driven supervised learning approach to identify gene network of differentially up-regulated genes during neuronal senescence in Rattus norvegicus , BioSystems, Elsevier,135,,9-14.
3 Meetei, Potshangbam Angamba., Singh, Pankaj., Nongdam, Potshangbam., Prabhu, N Prakash., Rathore, RS., Vindal, Vaibhav., (2012) , NeMedPlant: a database of therapeutic applications and chemical constituents of medicinal plants from north-east region of India , Bioinformation, Biomedical Informatics Publishing Group,8,4,209.
2 Arun, PV Parvati Sai., Bakku, Ranjith Kumar., Subhashini, Mranu., Singh, Pankaj., Prabhu, N Prakash., Suzuki, Iwane., Prakash, Jogadhenu SS., (2012) , CyanoPhyChe: a database for physico-chemical properties, structure and biochemical pathway information of cyanobacterial proteins , PloS one, Public Library of Science,7,11,e49425.
1 Singh, Pankaj., Suryavanshi, R., Sailu, S., Vindal, V., Kondapi, AK., Rathore, RS., (2010) , HIV Information REsources (HIRE): An Integrated Knowledgebase for Immunodeficiency Viruses , Proceedings of 2010 First International Conference on Cellular, Molecular Biology, Biophysics and Bioengineering (Volume 3), ,,,.
Title Year Duration Amount(In Lakhs) PI/I
A novel computational approach to generate genome based barcode intended to catalog Indian microbial species. 2020 5 68.6 Dr. Manjari Kiran, Dr. Pankaj S Dholaniya
DBT-Centre for Microbial Informatics (DBT-CMI) (approved by the Taskforce, DBT; awaiting financial sanction) 2020 5 200 Prof. H.A.Nagarajaram (Coordinator and PI), Prof. Appa Rao Podile (Co-PI), Prof. Dayananda Siddavattam (Co-PI), Prof. Ch Venkataramana (Co-PI), Dr. Pankaj Singh (Co-PI), Dr. Vivek (Co-PI), Dr. Manjari Kiran (Co-PI)
Modulating the expression of topo2b to enhance the viability of CGNs through genome editing 2018 3 59.2 Dr. Pankaj Singh Dholaniya



My research group is interested in investigating the mechanism and the molecular markers for neuronal senescence and age-associated neurodegenerative diseases. Currently, we are working towards the computational modeling of Parkinson’s disease from an integrated analysis of the GWAS, gene expression, proteome, and pathway data to explain the disease and non-disease states in term of the gene/protein interaction networks. We are also working on the characterization of the role of Topoisomerase 2 beta (Top2b) and its associated genes in neuronal senescence by modulating the expression of Top2b enzyme through genome editing techniques.

Genome Sequences:

7 Whole-genome sequences of Severe Acute Respiratory Syndrome Coronavirus 2 isolate (SARS-CoV-2) from Hyderabad, India#

  1. GenBank: MT415320.1; https://www.ncbi.nlm.nih.gov/nuccore/MT415320 
    GISAID: EPI_ISL_431101
  2. GenBank: MT415321.1; https://www.ncbi.nlm.nih.gov/nuccore/MT415321
    GISAID:EPI_ISL_431102
  3. GenBank: MT415322.1; https://www.ncbi.nlm.nih.gov/nuccore/MT415322 
    GISAID:EPI_ISL_431103
  4. GenBank: MT415323.1; https://www.ncbi.nlm.nih.gov/nuccore/MT415323 
    GISAID:EPI_ISL_431117
  5. GenBank: MT477885.1; https://www.ncbi.nlm.nih.gov/nuccore/MT477885 
    GISAID:EPI_ISL_438139
  6. GenBank: MT457402.1; https://www.ncbi.nlm.nih.gov/nuccore/MT457402 
    GISAID:EPI_ISL_437626
  7. GenBank: MT457403.1; https://www.ncbi.nlm.nih.gov/nuccore/MT457403 
    GISAID:EPI_ISL_438138

Tools and Databases:

  1. RTGR-TGV: Tomato genomic variation database#
    http://psd.uohyd.ac.in/tgv/

Microarray Datasets:

  1. E-MTAB-3977 - Transcription profiling by array of Human SUP-T1cells infected with HIV and/or treated with curcumin
    https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-3977/
  2. E-MTAB-4552 - Expression profiling of cerebellar granule neurons from Rattus norvegicus cultured for four week
    https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-4552/


#Work in collaboration


  • Computers and Programming
  • Machine learning methods and Data analytics
  • Database design and development
(For M.Tech Bioinformatics and integrated M.Sc. Systems Biology students)