Title Duration Amount (Lakhs) PI/I
Epigenetic Regulation of Nuclear Geometry: Studies on the existence of Symmetric and Asymmetric Physical Gene Networks in the Mammalian Cell Nucleus 1 year 3 Sreenivasulu Kurukuti
Dynamics of interactions between chromosomes and nuclear envelop 1 year 3 CO-PI
Structural and functional studies of glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase to understand their role in leishmaniasis 3 40.3 Insaf Ahmed Qureshi
Understanding the role of aminopeptidases in leishmaniasis through structural and functional studies 3 20 Insaf Ahmed Qureshi
Elucidate the biochemical role of Protein-Protein interaction in the post-transcriptional regulations 1 3.5 Insaf Ahmed Qureshi
Expression, purification and crystallographic studies of protein kinases from Plasmodium falciparum 3 24.9 Insaf Ahmed Qureshi
Identification, purification and characterization of protein phosphatases PP1 from Leishmania donovani 3 7.4 Insaf Ahmed Qureshi
Crystallographic study of casein kinase as structural-based target against malaria 1 3 Insaf Ahmed Qureshi
Studies on epigenetic gene regulation during lactation and its impact on milk biosynthesis 3 Years 74.8 Sreenivasulu Kurukuti
Polymorphic dynamics of RNAPII transcriptional nanostructures in Biological system 2 years 10 Sreenivasulu Kurukuti
Development and application of high-resolution chromatin interaction method for characterization of long-range chromatin interactions in the Eukaryotic system 3 Years 25.9 Sreenivasulu Kurukuti
Spatial transcriptional dynamics of miRNA coding genes in the maintenance of regulated gene expression patterns during cellular development and differentiation 3 Years 90 Sreenivasulu Kurukuti
Computational prioritization and experimental validation of novel regulators required for maintenance of Hematopoietic stem cells. Total budget 3 years 25 Sreenivasulu Kurukuti
Epigenetic mechanisms in embryonic stem cell pluripotency and differentiation 3 Years 48 Sreenivasulu Kurukuti
Development and application of high-resolution genome conformation capture technology to investigate genome architecture in space and time 2 Years 91 Sreenivasulu Kurukuti
Chemical and genomic approaches to investigate possible link between development of antimicrobial resistance (AMR) and pharma industry effluents 2 120 Prof. Dayananda Siddavatttam (PI), Prof. H.A.Nagarajaram (Co-PI), Prof. Ch Venkataramana (Co-PI)
Meiotic maturation of fish oocytes require steroidogenic shift: Interaction of hormone synthesizing enzyme and their transcriptional factors 3 21.29 Prof. B Senthilkumaran
Localization of GnRHs in brain during gametogenesis, and impacts of monoamines blockers and sex steroids on GnRH release using Indian habitat fish species 3 6.66 Prof. B Senthilkumaran
Molecular mechanisms of gonadal differentiation in fish tracing candidate marker genes to monitor germ cell proliferation and gametogenesis 3 24.673 Prof. B Senthilkumaran
Molecular mechanisms of Estreogen induced brain and gonadal differentiation in Indian habitat fish species 3 9 Prof. B Senthilkumaran
Identification of candidate genes/ susceptible to endocrine disruptors that affect reproduction: Functional genomics and proteomic approach 3 37.48 Prof. B Senthilkumaran
Ontogeny of monoaminergic system in the male and female brain of catfish and its input to gonadal development 3 19 Prof. B Senthilkumaran
Identification of transcription factors that play dual role to synchronize mesonephric and gonadal (urogenital) development in catfish 3 46.03 Prof. B Senthilkumaran
Evaluating nanotoxicity using food fish models of India 5 44.59 Prof. B Senthilkumaran
Sex manipulation in common carp and its hybrid using index major carp, rohu: genetic and molecular endocrinological approaches 3 55.72 Prof. B Senthilkumaran
Unravelling the role of fibroblast growth factors and signaling during gametogenesis in teleosts 3 19 Prof. B Senthilkumaran
Molecular characterization of genes/factors promoting testis growth and sperm maturation using teleosts fish models 3 77.89 Prof. B Senthilkumaran
Genome wide screen for tomato mutants by TILLING- Phase-II 5 270 Prof. R. P. Sharma
Program Support on Genome Engineering of Tomato 5 417 Prof. R. P. Sharma
Non-transgenic crop improvement of grain amaranth (A. hypochandriacus) for determinate growth, enhanced seed yield and oil by establishment of TILLING by sequencing platform 3 41 Prof. R. P. Sharma
Investigation on the mechanism of action of phytochrome in regulation of enzyme activity in higher plants 3 0.8 Prof. R. P. Sharma
Dissection of signal chain involved in phytochrome regulation of beta-amylase activity in mustard cotyledons 4 2.3 Prof. R. P. Sharma
Phytochrome regulation of membrane properties in higher plants 3 7.07 Prof. R. P. Sharma
Studies on Photoregulation and role of beta-amylase enzyme in photomorphogenesis of mustard cotyledon 3 1.7 Prof. R. P. Sharma
Isolation and characterization of phytochrome from green plant tissues 3 5.4 Prof. R. P. Sharma
Third World Academy of Sciences 1 0.15 Prof. R. P. Sharma
Regulation and role of leaf amylases in cereals 4 1.5 Prof. R. P. Sharma
Alexander von Humboldt Foundation, Bonn, Germany 1 1.8 Prof. R. P. Sharma
Analysis of photoperception and signal transmission in photomorphogenic mutants of higher plants 4 26.5 Prof. R. P. Sharma
Developmental gradients and photoregulation of enzymes in monocot leaves 4 7 Prof. R. P. Sharma
Volkswagen Foundation, Hanover, Germany. In Collaboration with University of Freiburg, Germany, Light-induced formation of components for protection against UV-B light in plants 3 40 Prof. R. P. Sharma
Molecular-genetic characterization of the cotyledon morphogenesis using tomato mutants 4 11 Prof. R. P. Sharma
Genetic and physical localization of the polycotyledon1 gene (poc) in tomato 4 2.71 Prof. R. P. Sharma
International Atomic Energy Agency, Vienna, Austria project entitled “Isolation and 5 19 Prof. R. P. Sharma
Molecular Analysis and Characterization of Phototropic Mutants of Tomato 4 24 Prof. R. P. Sharma
Functional genomics of tomato: Induced mutations as tool for manipulating fruit ripening 4 20 Prof. R. P. Sharma
Developmental regulation and functional analysis of PIN proteins in polycotyledon mutant of tomato 3 4.77 Prof. R. P. Sharma
International Atomic Energy Agency, Vienna, Austria project entitled Evaluation of effect of gamma radiation on targeted DNA sequence in tomato mutants. 7 19 Prof. R. P. Sharma
Molecular-genetic analysis of pattern formation in polycotyledon mutant of tomato 4 1.8 Prof. R. P. Sharma
Genetic manipulation of tomato for improvement in shelf life of fruits 5 55 Prof. R. P. Sharma
Genome wide screen for tomato mutants by TILLING 5 365 Prof. R. P. Sharma
International Atomic Energy Agency, Vienna, Austria project entitled “Search for Hypermutable Lines of Tomato by TILLING and EcoTILLING” 6 34 Prof. R. P. Sharma
Sequence-Indexed Library of Insertion Mutations in the Tomato Genome 5 253 Prof. R. P. Sharma
Biofortification of tomato by targeted manipulation of the biosynthetic pathways 8 1380 Prof. R. P. Sharma
Influence of phototropin genes on tomato fruit quality and shelf life 5 151 Yellamaraju Sreelakshmi
Manipulation of light signaling components for improvement of tomato fruit quality 5 144 Yellamaraju Sreelakshmi
Interaction between proteome and metabolome networks during tomato fruit ripening 8 154 Yellamaraju Sreelakshmi
Comparative proteomics of tomato versus wild relatives during fruit colouration 3 47.22 Yellamaraju Sreelakshmi
Mining for new alleles in tomato COP1 using EcoTILLING 3 8.94 Yellamaraju Sreelakshmi
Reverse Genetic Selection of Mutants for Manipulation of Carotenoids Level in Tomato, International Atomic Energy Agency, Vienna, Austria 6 3.35 Yellamaraju Sreelakshmi
Tomato fruit proteome analysis: a step towards understanding tomato genome 4 35.24 Yellamaraju Sreelakshmi
Role of signalosome in plant development: Isolation of COP1 mutants in tomato by TILLING 3 9.12 Yellamaraju Sreelakshmi
Membrane associated organophosphate (OPH) hydrolase complex in sphingobium fuliginis: determination of inter subunit interactions and elucidation of its role in acquisition of phosphate or iron. 3 58.5 Dayananda Siddavattam
Comprehensive omics studies on a versatile Sphingomonad strain to establish theoretical basis for in situ bioremediation of recalcitrant environmental pollutants. 2 57.9 Dayananda Siddavattam
Chemical and genomic approaches to investigate possible link between development of antimicrobial resistance (AMR) and pharma industry effluents. 3 100 Dayananda Siddavattam
Role of non-coding small RNAs (sRNA) in regulation of carbon catabolic pathways In E. coli 3 27.6 Dayananda Siddavattam
Discovery of gene missing components of regulatory network underlying C4 pathway/anatomy for translational research (Funding agency: DBT-ramalingaswami grant)) 5 88 Vivek
Modulating the expression of topo2b to enhance the viability of CGNs through genome editing 3 59.2 Dr. Pankaj Singh Dholaniya
12R-Lipoxygenase as a Target for Development of Drugs against Psoriasis 3 136 PI
Development of 12-LOX specific scoring function and Pharmacophore model: Design and biological evaluation of novel natural product derived inhibitors 3 63 PI
Establishment of BioNEST incubation center 5 500 PI
Basic Science Research Faculty Fellowship 5 33 PI
Nucleolus in control of breast tumor heterogeneity 3 94.97 Prof. Bramanandam Manavathi (PI); Prof. H.A.Nagarajaram (Co-PI)
Exploring the Volatome of NonCommunicable Diseases as a Promising Non-Invasive and Integrating Approach for its Rapid Diagnostics. The Case Study of Cancer and Neurodegenerative Diseases 3 32.11 Prof. H.A. Nagarajaram (Co-PI)
Host-virus interactions-DBT 3 52 Dr. M. Venkataramana/ Co PI- Dr. N. Prakash Prabhu, Department of Biotechnology and Bioinformatics
Elucidating the role of tyrosine phosphorylated proteins activated by lacritin in corneal epithelium 2 10 Roy Karnati
Understand the regulation of lacritin expression during infection and characterize molecular pathways induced by lacritin in corneal epithelium 2 35 Roy Karnati
Development of 5-LOX specific scoring function and application of fragment based free energy methods for the development of novel anti-cancer drug candidates 3 75 Roy Karnati
Characterization of corneal cell death during infection; Regulation and cytoprotective role of lacritin, an eye specific protein 3 30 Roy Karnati
Study of regulation of bacterial efflux pumps by cyclooxygenase-2 inhibitor, celecoxib. 3 41 PI
Identification and characterization of posttranslational modifications of HDAC4 3 30 PI
celecoxib in combination with antibiotics on clinically isolated bacterial strains and in Mouse model of Sepsis 3 61 PI
Study of regulation of ABC transporters by cyclooxygenase-2 (COX-2) and use of COX-2 inhibitors in reversal of drug resistance by ABC transporters 3 23 PI
Exploration of antibacterial, immunomodulatory and anti-inflammatory activity of certain polyphenolic compounds and role of NSAIDs on activity of antibiotics 3 23 PI
Molecular Dynamics Studies of the HDAC8 isoform, Virtual Screening of Potential HDAC8 Inhibitors using Structure and Ligand Based Studies – Synthesis and Biological Screening of Novel HDAC8 inhibitors 3 21 PI
Role of Histone deacetylases (HDACs) in Maintenance of Inactive X chromosome (Xi) 3 54.4 PI
Identification of candidate leptospiral antigens and host-specific biomarkers for the diagnosis and management of leptospirosis 3 51 Prof. Manjula Sritharan
Understanding the role of HupB as an adhesion molecule:implications in extrapulmonary tuberculosis 3 35 Prof. Manjula Sritharan
Epigenomic pathways orchestrating cell development and function 1 3.5 Prof. Manjula Sritharan
Interaction of the iron-regulated protein HupB of Mycobacterium tuberculosis with Fe3 - high affinity siderophores and synthesis of mycobactin T and analogues 2 4.4 Prof. Manjula Sritharan
Development of multiplex PCR and Real Time PCR assay systems for the identification of Methicillin Resistant Staphylococcus aureus (MRSA) 3 25 Prof. Manjula Sritharan
Sero-diagnosis of leptospirosis: development and validation of immunoassays for the detection of anti-leptospiral antibodies in serum samples 3 31.7 Prof. Manjula Sritharan
Virtual Centre of Excellence on multi-disciplinary approaches aimed at interventions against Mycobacterium tuberculosis 5 44.7 Prof. Manjula Sritharan
DNA microarray analysis for the identification of molecular markers in Mycobacterium tuberculosis expressed during iron limitation and latency Multi-departmental project of UoH 4 15 Prof. Manjula Sritharan
Anti-tubercular compounds targeting the iron-acquisition machinery of M. tuberculosis (Joint project with Prof. SubhashPadhye (SP), Univ.of Pune) 4 31.9 Prof. Manjula Sritharan
Virulence factors of Leptospira 4 28.82 Prof. Manjula Sritharan
HbpA, a novel hemin-binding protein as a serodiagnostic agent for leptospirosis 1 4.98 Prof. Manjula Sritharan
Studies on plasma iron levels in patients with tuberculosis and in vivo expression of iron-regulated proteins in Mycobacterium tuberculosis 3 10.6 Prof. Manjula Sritharan
Biochemical evaluation of iron deprivation in Mycobacterium tuberculosis with specific reference to iron-regulated envelope proteins and to action of anti-mycobacterial drugs 3 14.67 Prof. Manjula Sritharan
Iron, catalase and INH activation in M. tuberculosis 3 11.96 Prof. Manjula Sritharan
Diagnostic potential of the culture filtrate antigens of M. tuberculosis 1 2.7 Prof. Manjula Sritharan
Iron deprivation in pathogenic Leptospira spp.: identification and characterization of iron-regulated membrane proteins 2 22 Prof. Manjula Sritharan
Iron deprivation in pathogenic Leptospira spp.: identification and characterization of iron-regulated membrane proteins 3 8.28 Prof. Manjula Sritharan
Antibodies against the iron-regulated envelope proteins in M. bovis BCG 2 0.2 Prof. Manjula Sritharan
Diagnosis and development of vaccines against cattle diseases caused by Mycobacterium bovis and leptospires 3 64.93 Prof. Manjula Sritharan
Host-virus interactions - SERB 3 55 Dr. M. Venkataramana/ Co PI - Dr. Kota Arun Kumar, Department of Animal Biology
Host-virus interactions - MHRD-IISC STARS 3 99 Dr. M. Venkataramana/ Co PI- Prof. Naresh Babu V. Sepuri, Department of Biochemistry
Hypoxia Alters Calcium Influx in the Glomerular Podocytes: Implications in Cytoskeletal Derangement and Proteinuria 3 60 P Anil Kumar
Assessment of antimicrobial and plant growth promoting potential of indigenous endophytic bacterial strains of Manipur” under DBT’s Twinning Programme for NER (No. BT/PR25395/NER/95/1177/2017) 3 years 15.3 Prof. Sharmistha Banerjee
Identification and Characterization of mycobacterial factors supporting HIV propagation during HIV-mycobacteria co-infection (BT/HRD/NWBA/38/09/2018) 5 years 25 Prof. Sharmistha Banerjee
Design and Development of novel antitubercular agents targeting Shikimate kinase protein” under DBT (No. BT/PR23619/MED/29/1199/2017, dated 09.01.2018) 3 years 21.6 Prof. Sharmistha Banerjee
Centre of Excellence in Biomolecular structure and function on Host-Pathogen interaction (BT/PR15450/COE/34/46/2016) 5 years 76.11 Prof. Sharmistha Banerjee
Environmental stress responses in protein structure and metabolism of plant and algal chloroplasts 3 173 S Rajagopal
Genetic manipulation of ripening-associated ERFs for the regulation of ripening in tomato 5 35 PI
Investigations on the carotenoids level in tomato genotypes with altered ethylene signalling 1 3.5 PI
Creation of a genetic resource of ........fruit ripening and phosphate starvation response 3 20 PI
Engineering of ................ traits in tomato 3 40.83 PI
Understanding genetic diversity ..... to low phosphate in tomato 3 35 PI
Exploring the natural .. for phosphate starvation responses 2 11.82 PI
Redox constraints regulate photorespiration 3.5 93.82 Prof. A. S. Raghavendra
Engineering Photosynthesis in Mulberry for Resilience to Climate Change: A C4 Approach 4 23.37 Prof. A. S. Raghavendra
Modulation of Photorespiration by Oxidative Stress: Role of Oxygen and Reactive Nitrogen Species 3 36.48 Prof. A. S. Raghavendra
Identification of novel alleles of wild rice derived bacterial blight resistance genes and their functional analysis 3 Years 29.59 PI
Transcriptome dynamics during drought stress in foxtail millet 5 35 M Muthamilarasan
Reducing antinutritional traits in millets using next-gen genomics approaches 3 33 M Muthamilarasan
Role of Topoisomerase VI in the biology of malaria parasite 3 72.28 Sunanda Bhattacharyya (PI)
Role of Hsp90 in Rad51 mediated DNA repair 3 15.5 Sunanda Bhattacharyya (PI)
Structure function relationship of Hsp90 in yeast telomere 3 40 Sunanda Bhattacharyya (PI)
Cloning and characterization of Plasmodium falciparum Topoisomerase VI 3 30 Sunanda Bhattacharyya (PI)
Understanding the role of homologous recombination in genomic rearrangements leading to antigenic diversification in malaria parasites 3 49.3 Sunanda Bhattacharyya (Co-PI)
To study the role of Hsp90 in DNA double strand break repair pathway 1 3 Sunanda Bhattacharyya (PI)
Role of proteins and protein aggregates in cellular physiology and disease progression 1 3 Sunanda Bhattacharyya (Co-PI)
Long non-coding RNA Regulation: Role in megakaryocyte development 3 18 PI
From small to big: microRNAs as new players in developmental megakaryocytopoiesis 3 46.6 PI
Toll-like Receptor Signalling: Significance in Megakaryocyte Development and Platelet Production 3 46.2 PI
SETDB1 in hematopoiesis and hematopoietic tumors: Target genes and their regulation 3 30 Mentor
Molecular regulation of the differences between neonatal and adult megakaryocytopoiesis leading to bleeding disorders 3 25 PI
Potential signaling pathways in molecular regulation of different developmental stages of human megakaryocytes 3 52.9 PI
Identification and characterization of novel microRNA of clinical importance from neonatal and adult derived megakaryocytes 3 9.6 PI
miR-9/Runx1 mediates developmental regulation of distinct megakaryocytopoiesis 3 33.25 PI
Role of Toll-like Receptor Signaling Mediated Disease Resistance in Indian Poultry 3 27.25 PI
Potential role of miR-9 regulation in CXCR-4 expression at different developmental stages of human megakaryocytes 4 41.81 PI
Centre of Excellence in Biomolecular Structure and Function on Host Pathogen Interactions 5 69.8 Krishnaveni Mishra
Role of SUMOylation in virulence of Candida glabrata 3 48.028 Krishnaveni Mishra
Identification of the SUMOylation target in yeast heterochromatin 3 20 Krishnaveni Mishra
Enzyme cascade biocatalysis in the stereoselective synthesis of chiral intermediates 3 20 Santosh Kumar Padhi
Quantitative proteomics of Protein Body components (lectins and glycosidases), from the Trichosanthes anguina seeds: elucidation of protein-protein interactions in the protein body biogenesis 2 Years 10 Prof. N. Siva Kumar
Biochemical investigation of endosomal targeting proteins and functional analysis of lysosomal enzymes and their receptors in Hydra 3 Years 58 Prof. N. Siva Kumar
Growth hormone mediates glomerular podocyte hypertrophy: Implications in diabetic nephropathy 3 18 P. Anil Kumar
Hypoxia-mediated epithelial-mesenchymal transition 3 38 P. Anil Kumar
Prevention of epithelial-mesenchymal transition of podocytes by inhibition of natural antisense transcript for ZEB2: Implications for prevention of diabetic nephropathy 3 51 P. Anil Kumar
Novel Non-Canonical Role of Growth hormone on Glomerular Podocytes 5 68 P. Anil Kumar
Role of Growth hormone on Mammary Epithelial Carcinoma 3 18 P. Anil Kumar
Growth hormone induces IL-17 in glomerular podocytes: Implications in the pathogenesis of diabetic nephropathy 3 30 P. Anil Kumar
Silica-induced Nephrotoxicity: Implications in Uddanam Kidney Disease of Unknown Origin 3 50 P. Anil Kumar
The role of WT1 in Obesity-related glomerulonephropathy 3 80 P. Anil Kumar
Identification of gender-specific prognostic genes in 27 human cancers. 2 7.94 Dr. Manjari Kiran
A novel computational approach to generate genome based barcode intended to catalog Indian microbial species. 5 68.6 Dr. Manjari Kiran, Dr. Pankaj S Dholaniya
1. Regulatory functions of microRNAs during early lymphoid lineage differentiation 3 57 Jagan Pongubala
2. Cis-regulatory configuration controlling B-lineage gene expression 3 70 Jagan Pongubala