Faculty Details

Faculty Details

  • Name: Dr. Irfan Ahmad Ghazi
  • Mail: irfanuohyd.ernet.in
  • Contact: 91-40-23134511
  • Area Of Research:Rice functional Genomics for BLB resistance,

We are working on allele mining of candidate R-genes in different cultivated and wild rice genotypes for bacterial leaf blight (BLB) disease. We are looking for novel/superior alleles of important BLB R-genes and studying their expression pattern in BLB resistance germplasms. Understanding of functional differences among alleles will help in deciphering its structure and function and finally facilitate easy identification of superior alleles corresponding to avr gene. We are interested in the functional validation of these genes which would reveal the mechanisms of resistance and support further exploitation to enhance the breadth of resistance in rice against bacterial blight.We are using genomics, proteomics and metabolomics approaches to understand the mechanism of disease. Our ultimate aim is to introduce the selected R-genes into the most popular cultivated variety(ies) of rice and in crop improvement program at global level.

Apart from rice functional genomics, my research group is also focused on isolation and characterization and understanding of bioactive compounds from Rice bran and potent medicinal plants used in Indian tradition system. The anti-oxidative phytochemicals in grains, vegetables, fruits and medicinal plants have received increasing attention for their potential role in prevention of human diseases. Presently, our lab is working on understanding the biological activities of Artemisia nilagirica and Rice Bran for their therapeutic property with special reference to anticancer activities. 

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Students/Projects Trainees

Name Joined As Mail Contact
Ms. Rutuparna Jena PhD Student jenarutuparna1990@gmail.com 8074734904
Mr. Raj Kishor Sahoo PhD Student raj15.uubot@gmail.com 7504741191
Ms. Prajna priyadarshini PhD Student prajnapriyadarshinidas97@gmail.com 7377668657

Former Students/Projects Trainees

Name Joined As Working
Dr. Anirudh Kumar Worked as PhD Assistant Professor, Indira Gandhi National Tribal University, Amarkantak, MP
Dr. Mir Zahoor Gul Worked as PhD UGC-Kothari Fellow at Osmania University, Hyderabad
Dr. Waikom Bimolata Worked as PhD Student
Dr. Mohd. Yasin Bhat Worked as PhD Student
24 Mujeeb, Anzar Abdul., Alam, Khan Farheen Badre., Alshameri, Ansam Wadia Faid., Jamal, Fauzia., Farheen, Saba., Kashif, Mohd., Ahmed, Anees., Ghazi, Irfan Ahmad., Owais, Mohammad., (2019) , Chaperone Like Attributes of Biogenic Fluorescent Gold Nanoparticles: Potential to Alleviate Toxicity Induced by Intermediate State Fibrils Against Neuroblastoma Cells , Frontiers in Chemistry, Frontiers Media SA,7,,.
23 Gul, MZ., Bhat, MY., Maurya, R., Qureshi, IA., Ghazi, IA., (2018) , In vitro evaluation of antioxidant and antiproliferative activities of Artemisia nilagirica extracts , Indian Journal of Pharmaceutical Sciences, OMICS International,79,6,872-884.
22 Gul, MZ., Manjulatha, K., Bhat, MY., Maurya, R., Qureshi, IA., Ghazi, IA., (2018) , Antiproliferative and apoptosis-inducing effects of Abrus precatorius against human monocytic leukaemia (THP-1) cell line , Indian Journal of Pharmaceutical Sciences, OMICS International,80,2,307-317.
21 Bhat, Mohd Yasin., Gul, Mir Zahoor., Maurya, Radheshyam., Khan, Nooruddin., Qureshi, Insaf Ahmed., Ghazi, Irfan Ahmad., (2018) , Growth inhibition and apoptosis inducing effects of Artemisia absinthium L. fractions on chronic myeloid leukemia (K562) cells , Journal of Biologically Active Products from Nature, Taylor & Francis,8,2,70-89.
20 Bhat, Mohd Yasin., Gul, Mir Zahoor., Khan, Nooruddin., Qureshi, Insaf Ahmed., Ghazi, Irfan Ahmad., (2017) , Cytoprotective activity and anti-inflammatory properties of Artemisia nilagirica (Clarke) extracts-A study with macrophages , Journal of Biologically Active Products from Nature, Taylor & Francis,7,3,228-244.
19 Manjulatha, K., Gul, Mir Z., Imam, Nasir., Ghazi, Irfan A., Setty, Oruganti H., (2016) , Phytochemical content and antioxidant potential of Clerodendrum inerme and its different parts-A comparative study , Journal of Biologically Active Products from Nature, Taylor & Francis,6,1,65-77.
18 Gul, Mir Zahoor., Chandrasekaran, Sambamurthy., Bhat, Mohd Yasin., Maurya, Radheshyam., Qureshi, Insaf Ahmed., Ghazi, Irfan Ahmad., (2016) , Bioassay-guided fractionation and in vitro antiproliferative effects of fractions of Artemisia nilagirica on THP-1 cell line , Nutrition and cancer, Taylor & Francis,68,7,1210-1224.
17 Ghazi, IA., Zarei, I., Mapesa, JO., Wilburn, JR., Leach, JE., Rao, S., Broeckling, C., McClung, AM., Ryan, EP., (2016) , Rice bran extracts inhibit invasion and intracellular replication of Salmonella typhimurium in mouse and porcine intestinal epithelial cells , Med Aromat Plants (Los Angel), ,5,271,2167-0412.1000271.
16 Kumar, Anirudh., Bimolata, Waikhom., Kannan, Monica., Kirti, PB., Qureshi, Insaf Ahmed., Ghazi, Irfan Ahmad., (2015) , Comparative proteomics reveals differential induction of both biotic and abiotic stress response associated proteins in rice during Xanthomonas oryzae pv. oryzae infection , Functional & integrative genomics, Springer Berlin Heidelberg,15,4,425-437.
15 Bimolata, Waikhom., Kumar, Anirudh., Sundaram, Raman Meenakshi., Laha, Gouri Sankar., Qureshi, Insaf Ahmed., Ghazi, Irfan Ahmad., (2015) , Nucleotide diversity analysis of three major bacterial blight resistance genes in rice , PLoS One, Public Library of Science,10,3,e0120186.
14 Kumar, Anirudh., Guha, Anirban., Bimolata, Waikhom., Reddy, Attipalli R., Laha, Gouri S., Sundaram, RM., Pandey, Manish K., Ghazi, Irfan A., (2013) , Leaf gas exchange physiology in rice genotypes infected with bacterial blight: An attempt to link photosynthesis with disease severity and rice yield , Australian Journal of Crop Science, Southern Cross Publishers,7,1,32.
13 Gul, Mir Z., Ahmad, Farhan., Kondapi, Anand K., Qureshi, Insaf A., Ghazi, Irfan A., (2013) , Antioxidant and antiproliferative activities of Abrus precatorius leaf extracts-an in vitro study , BMC Complementary and Alternative Medicine, BioMed Central,13,1,1-12.
12 Bimolata, Waikhom., Kumar, Anirudh., Sundaram, Raman Meenakshi., Laha, Gouri Shankar., Qureshi, Insaf Ahmed., Reddy, Gajjala Ashok., Ghazi, Irfan Ahmad., (2013) , Analysis of nucleotide diversity among alleles of the major bacterial blight resistance gene Xa27 in cultivars of rice (Oryza sativa) and its wild relatives , Planta, Springer Berlin Heidelberg,238,2,293-305.
11 Kumar, Anirudh., Gul, Mir Zahoor., Zeeshan, Ayesha., Bimolata, Waikhom., Qureshi, Insaf Ahmed., Ghazi, Irfan Ahmad., (2013) , Differential antioxidative responses of three different rice genotypes during bacterial blight infection , Australian Journal of Crop Science, Southern Cross Publishers,7,12,1893.
10 Gul, Mir Z., Bhakshu, Lepakshi M., Ahmad, Farhan., Kondapi, Anand K., Qureshi, Insaf A., Ghazi, Irfan A., (2011) , Evaluation of Abelmoschus moschatus extracts for antioxidant, free radical scavenging, antimicrobial and antiproliferative activities using in vitro assays , BMC complementary and alternative medicine, BioMed Central,11,1,64.
9 Ghazi, Irfan A., Srivastava, Prem S., Dalal, Vivek., Gaikwad, Kishor., Singh, Ashok K., Sharma, Tilak R., Singh, Nagendra K., Mohapatra, Trilochan., (2009) , Physical mapping, expression analysis and polymorphism survey of resistance gene analogues on chromosome 11 of rice , Journal of biosciences, Springer-Verlag,34,2,251-261.
8 Yadava, DK., Parida, Swarup K., Dwivedi, VK., Varshney, A., Ghazi, Irfan A., Sujata, V., Mohapatra, T., (2009) , Cross-transferability and polymorphic potential of genomic STMS markers of Brassica species , Journal of plant biochemistry and biotechnology, Springer India,18,1,29-36.
7 Mueller, Lukas A Lankhorst., Tanksley, René Klein., Giovannoni, Steven D., White, James J., Vrebalov, Ruth., Fei, Julia., van Eck, Zhangjun., Buels, Joyce., Mills, Robert., Menda, Adri A., (2009) , A snapshot of the emerging tomato genome sequence , The Plant Genome, Crop Science Society of America,2,1,78.
6 Singh, Nagendra K., Dalal, Vivek., Batra, Kamlesh., Singh, Binay K., Chitra, G., Singh, Archana., Ghazi, Irfan A., Yadav, Mahavir., Pandit, Awadhesh., Dixit, Rekha., (2007) , Single-copy genes define a conserved order between rice and wheat for understanding differences caused by duplication, deletion, and transposition of genes , Functional & integrative genomics, Springer-Verlag,7,1,17-35.
5 Singh, Nagendra K., Dalal, Vivek., Batra, Kamlesh., Singh, Archana., Yadav, Mahavir., Dixit, Rekha., Ghazi, Irfan A., Pandit, Awadhesh., (2007) , Comparative Analysis of Rice and Wheat Genomes as a Tool for Gene Discovery , Science, Technology, and Trade for Peace and Prosperity, Int. Rice Res. Inst.,,,121.
4 Kanwar, SS., Ghazi, IA., Chimni, SS., Joshi, GK., Rao, GV., Kaushal, RK., Gupta, R., Punj, V., (2006) , Purification and properties of a novel extra-cellular thermotolerant metallolipase of Bacillus coagulans MTCC-6375 isolate , Protein expression and purification, Academic Press,46,2,421-428.
3 Sasaki, Takuji., (2005) , The map-based sequence of the rice genome , Nature, Nature Publishing Group,436,7052,793-800.
2 Rice Chromosomes 11 and 12 Sequencing Consortia* messing@ waksman. rutgers. edu., (2005) , The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications , BMC biology, BioMed Central,3,,1-18.
1 Singh, Nagendra K., Raghuvanshi, Saurabh., Srivastava, Subodh K., Gaur, Anupama., Pal, Ajit K., Dalal, Vivek., Singh, Archana., Ghazi, Irfan A., Bhargav, Ashutosh., Yadav, Mahavir., (2004) , Sequence analysis of the long arm of rice chromosome 11 for rice–wheat synteny , Functional & integrative genomics, Springer-Verlag,4,2,102-117.
Title Year Duration Amount(In Lakhs) PI/I
Engineering of ................ traits in tomato 2019 3 40.83 PI
Identification of novel alleles of wild rice derived bacterial blight resistance genes and their functional analysis 2018 3 Years 29.59 PI