This workshop will be considered as an elected course (2 credits) for M.Sc students, School Life Sciences, UOH.
Interested students should register for this workshop as early as possible.

Welcome to GIAN Workshop

Overview

           Lipid mediators are important signalling molecules, which have been implicated in many physiological and pathological processes both in plants and animals. Lipid mediators, biosynthesized from lipid precursors by the catalytic activity of various enzymes, are delivered into the extracellular space to stimulate surrounding cells by binding to specific cell surface receptors. Alternatively they are delivered into the blood stream and transported to distant organs to alter the functional phenotype of selected cells. Lipid mediators do also function as intercellular second messengers (diacylglycerols, sphingolipids), which are biosynthesized in response to agonist induced cell activation to trigger intracellular signaling cascades. The structural and functional multiplicity of lipid signaling molecules and their implication in a large variety of physiologically and patho-physiologically relevant signaling cascades has put the research on lipid mediators into the focus of current pharmacological reaserch. The search for inhibitors of lipid mediator biosynthesis (COX2 inhibitors, ALOX5 inhibitors) and for lipid mediator receptor antagionists (cysteinyl leukotriene-receptor 1 antagonists, endocannabonoidreceptor-Agonists) has already led to the development of drugs prescribed for the treatment of severe systemic inflammation, bronchial asthma and pain. Intense search is currently going on to develop inhibitors and receptor antagonists against these targets.
           Similarly lipid mediators in plants play an important role in the regulation of growth and development, fruit ripening and senescence, wound healing and defence against injury and infection. Some of these include molecules such as fatty acid hydroperoxy and hydroxy metabolites, jasmonic acid, traumatin, hexenols, nonenals etc.

Coordinators:

Prof. Pallu Reddanna:

Dean, School of Life Sciences, UoH Img

Prof. A.R Reddy:

Department of Plant Sciences, School of Life Sciences, UoH Img

Dr. Rajagopal:

Department of Plant Sciences, School of Life Sciences, UoH Img

Objectives:

The primary objectives of the course are as follows:
  1. Exposing participants to the fundamentals of lipid signaling in health and disease in plants and animals and characterization of position of the field in current biomedical research.
  2. Identifying hot topics in current lipid signaling research with particular emphasis on the possibility of pharmacological interference and on strategies of future drug develeopment.
  3. Identification of innovative molecular drug targets (enzymes, receptors) as well as functional and structural characterization of these proteins and their potential interactions with regulative partners.
  4. Understanding the role of lipid signaling in plants in the regulation of normal physiological processes as well as in injury and pathogen defence.
  5. Enhancing the capability of the participants to identify, control and remove lipid signaling-related problems in cellular and supra-cellular systems.
  6. Establishing personal connections and providing the basis for future international collaborations in lipid signaling to include Indian scientists into multi-national collaborative research networks financed by public and private international funding institutions.
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Note:

Payment can be made on the spot if you are facing any difficulty in paying the registration fee in favour of GIAN Lipid for University of Hyderabad. Also, I suggest you to submit the filled registration form as early possible (before 24th November, 2016) to ensure your participation by post or email.